Price range: $268.00 through $328.00
Background:
This gene encodes an immunoglobulin-like cell surface protein that is expressed predominantly on plasmacytoid dendritic cells (PDCs) and modulates the function of these cells in the immune response. Expression of this gene is downregulated by interleukin 3 (IL3). This gene is one of a cluster of highly related genes located at chromosomal region 19q13.4. [provided by RefSeq, Jan 2015],
| Size | 50μL/100μL |
| Target | CD85g |
| Reactivity | Human |
| Applications | WB, IHC, IF, ELISA |
| MW(Calculated) | |
| MW(Observed) | 55kD |
| Host Species | Rabbit |
| Isotype | IgG |
| Conjugate/Modification | Unmodified |
| Recommended Dilution Ratio | WB 1:500-1:2000; IHC: 1:100-300; ELISA 1:20000; IF 1:50-200 / Note: For IHC, we suggest antigen retrieval with TE buffer pH 9.0 (Cat#WT1004) |
| Formulation | Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide. |
| Purification | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Storage | -15°C to -25°C/1 year(Do not lower than -25°C) |
| Concentration | 1 mg/ml |
| Clonality | Polyclonal |
| Clone Number | |
| Immunogen | The antiserum was produced against synthesized peptide derived from the Internal region of human LILRA4. AA range:391-440 |
| Specificity | CD85g Polyclonal Antibody detects endogenous levels of CD85g protein. |
| Gene Name | LILRA4 |
| Protein Name | Leukocyte immunoglobulin-like receptor subfamily A member 4 |
| Other Name | LILRA4; / ILT7; / Leukocyte immunoglobulin-like receptor subfamily A member 4; / CD85 antigen-like family member G; / Immunoglobulin-like transcript 7; / ILT-7; / CD85g |
| Species | Human |
| Gene ID | 23547 |
| Uniprot | P59901 |
| Species.1 | |
| Gene ID.1 | |
| Uniprot.1 | |
| Species.2 | |
| Gene ID.2 | |
| Uniprot.2 | |
| Cellular Localization | Cell membrane; Single-pass type I membrane protein . |
| Tissue Expression | Detected on plasmacytoid dendritic cells (at protein level). Detected on plasmacytoid dendritic cells, but not on monocytes or B cells. |
| Signaling_pathway | Organismal Systems >> Immune system >> B cell receptor signaling pathway;Organismal Systems >> Development and regeneration >> Osteoclast differentiation |
| Research Areas | >>Osteoclast differentiation; / >>B cell receptor signaling pathway |
| Function | Function:May act as receptor for class I MHC antigens. Ligand binding leads to the activation of eosinophils and to the release of RNASE2, IL4 and leukotriene C4.,similarity:Contains 4 Ig-like C2-type (immunoglobulin-like) domains.,tissue specificity:Detected on eosinophils, neutrophils and monocytes., |
