Price range: $268.00 through $328.00
Background:
CDNF (Cerebral Dopamine Neurotrophic Factor) is a Protein Coding gene. Trophic factor for dopamine neurons. Prevents the 6-hydroxydopamine (6-OHDA)-induced degeneration of dopaminergic neurons. When administered after 6-OHDA-lesioning, restores the dopaminergic function and prevents the degeneration of dopaminergic neurons in substantia nigra (By similarity).
| Size | 50μL/100μL |
| Target | CDNF |
| Reactivity | Human, Mouse, Rat |
| Applications | IHC, IF, ELISA |
| MW(Calculated) | |
| MW(Observed) | |
| Host Species | Rabbit |
| Isotype | IgG |
| Conjugate/Modification | Unmodified |
| Recommended Dilution Ratio | IHC 1:50-200; ELISA 1:10000-20000; IF 1:50-200 / Note: For IHC, we suggest antigen retrieval with TE buffer pH 9.0 (Cat#WT1004) |
| Formulation | Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide. |
| Purification | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Storage | -15°C to -25°C/1 year(Do not lower than -25°C) |
| Concentration | 1 mg/ml |
| Clonality | Polyclonal |
| Clone Number | |
| Immunogen | Synthetic peptide from human protein at AA range: 31-80 |
| Specificity | The antibody detects endogenous CDNF |
| Gene Name | CDNF ARMETL1 |
| Protein Name | Cerebral dopamine neurotrophic factor (ARMET-like protein 1) (Conserved dopamine neurotrophic factor) |
| Other Name | Cerebral dopamine neurotrophic factor; / ARMET-like protein 1; / Conserved dopamine neurotrophic factor |
| Species | Human |
| Gene ID | 441549 |
| Uniprot | Q49AH0, |
| Species.1 | Mouse |
| Gene ID.1 | 227526 |
| Uniprot.1 | Q8CC36 |
| Species.2 | |
| Gene ID.2 | |
| Uniprot.2 | |
| Cellular Localization | Secreted . |
| Tissue Expression | Widely expressed in neuronal and non-neuronal tissues. In the brain, highest levels in the optic nerve and corpus callosum. |
| Signaling_pathway | |
| Research Areas | |
| Function |
