CE120 rabbit pAb
Ucallm_WP16482-50
Price range: $268.00 through $328.00
Product details
Background:
This gene encodes a protein that functions in the microtubule-dependent coupling of the nucleus and the centrosome. A similar protein in mouse plays a role in both interkinetic nuclear migration, which is a characteristic pattern of nuclear movement in neural progenitors, and in neural progenitor self-renewal. Mutations in this gene are predicted to result in neurogenic defects. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Oct 2009],
Specifications
| Size | 50μL/100μL |
| Target | CE120 |
| Reactivity | Human, Mouse |
| Applications | WB |
| MW(Calculated) | 108kD |
| MW(Observed) | |
| Host Species | Rabbit |
| Isotype | IgG |
| Conjugate/Modification | Unmodified |
| Recommended Dilution Ratio | WB 1:500-2000 |
| Formulation | Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide. |
| Purification | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Storage | -15°C to -25°C/1 year(Do not lower than -25°C) |
| Concentration | 1 mg/ml |
| Clonality | Polyclonal |
| Clone Number | |
| Immunogen | Synthesized peptide derived from human CE120 AA range: 335-385 |
| Specificity | This antibody detects endogenous levels of CE120 at Human/Mouse |
| Gene Name | CEP120 CCDC100 |
| Protein Name | CE120 |
| Other Name | |
| Species | Human |
| Gene ID | 153241 |
| Uniprot | Q8N960, |
| Species.1 | Mouse |
| Gene ID.1 | 225523 |
| Uniprot.1 | Q7TSG1 |
| Species.2 | |
| Gene ID.2 | |
| Uniprot.2 | |
| Cellular Localization | Cytoplasm, cytoskeleton, microtubule organizing center, centrosome . Regulates the localization of TACC3 to the centrosome in neural progenitors in vivo. . |
| Tissue Expression | |
| Signaling_pathway | |
| Research Areas | |
| Function | Function:Plays a role in the microtubule-dependent coupling of the nucleus and the centrosome. Involved in the processes that regulate centrosome-mediated interkinetic nuclear migration (INM) of neural progenitors and for proper positioning of neurons during brain development. Also implicated in the migration and selfrenewal of neural progenitors.,similarity:Belongs to the CEP120 family.,subcellular location:Regulates the localization of TACC3 to the centrosome in neural progenitors in vivo.,subunit:Interacts with TACC2 and TACC3., |
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