CHIC2 rabbit pAb
Ucallm_WP4169-50
Price range: $268.00 through $328.00
Product details
Background:
This gene encodes a member of the CHIC family of proteins. The encoded protein contains a cysteine-rich hydrophobic (CHIC) motif, and is localized to vesicular structures and the plasma membrane. This gene is associated with some cases of acute myeloid leukemia. [provided by RefSeq, Jul 2008],
Specifications
| Size | 50μL/100μL |
| Target | CHIC2 |
| Reactivity | Human, Mouse |
| Applications | WB |
| MW(Calculated) | 18kD |
| MW(Observed) | |
| Host Species | Rabbit |
| Isotype | IgG |
| Conjugate/Modification | Unmodified |
| Recommended Dilution Ratio | WB 1:500-2000 |
| Formulation | Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide. |
| Purification | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Storage | -15°C to -25°C/1 year(Do not lower than -25°C) |
| Concentration | 1 mg/ml |
| Clonality | Polyclonal |
| Clone Number | |
| Immunogen | Synthesized peptide derived from human CHIC2 AA range: 111-161 |
| Specificity | This antibody detects endogenous levels of CHIC2 at Human/Mouse |
| Gene Name | CHIC2 BTL |
| Protein Name | CHIC2 |
| Other Name | |
| Species | Human |
| Gene ID | 26511 |
| Uniprot | Q9UKJ5, |
| Species.1 | Mouse |
| Gene ID.1 | 74277 |
| Uniprot.1 | Q9D9G3 |
| Species.2 | |
| Gene ID.2 | |
| Uniprot.2 | |
| Cellular Localization | Cell membrane . Cytoplasmic vesicle . Also present at a Golgi-like vesicular compartment and at scattered vesicles. |
| Tissue Expression | |
| Signaling_pathway | |
| Research Areas | |
| Function | Disease:A chromosomal aberration involving CHIC2 is found in a form of acute myeloid leukemia (AML). Translocation t(4; 12)(q12; p13) with ETV6.,PTM:Palmitoylation in the CHIC motif is required for membrane association.,similarity:Belongs to the CHIC family.,subcellular location:Also present at a Golgi-like vesicular compartment and at scattered vesicles., |
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