SKU: WP11630 Categories: ,

CHST9 Polyclonal Antibody

Price range: $268.00 through $328.00

SKU: WP11630-100
Enter the quantity you would like, or drag the panel to find the quantity and price that best for you
Bulk QuoteAuthorize OEM & ODM

Product details

Background:

The protein encoded by this gene belongs to the sulfotransferase 2 family. It is localized to the golgi membrane, and catalyzes the transfer of sulfate to position 4 of non-reducing N-acetylgalactosamine (GalNAc) residues in both N-glycans and O-glycans. Sulfate groups on carbohydrates confer highly specific functions to glycoproteins, glycolipids, and proteoglycans, and are critical for cell-cell interaction, signal transduction, and embryonic development. Alternatively spliced transcript variants have been described for this gene. [provided by RefSeq, Aug 2011],

Specifications

Size50μL/100μL
TargetCHST9
ReactivityHuman, Mouse
ApplicationsIHC, IF, ELISA
MW(Calculated)51kD
MW(Observed)
Host SpeciesRabbit
IsotypeIgG
Conjugate/ModificationUnmodified
Recommended Dilution RatioIHC 1:100-1:300; IF 1:200-1:1000; ELISA 1:20000; Not yet tested in other applications. / Note: For IHC, we suggest antigen retrieval with TE buffer pH 9.0 (Cat#WT1004)
FormulationLiquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
PurificationThe antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Storage-15°C to -25°C/1 year(Do not lower than -25°C)
Concentration1 mg/ml
ClonalityPolyclonal
Clone Number
ImmunogenThe antiserum was produced against synthesized peptide derived from human CHST9. AA range:361-410
SpecificityCHST9 Polyclonal Antibody detects endogenous levels of CHST9 protein.
Gene NameCHST9
Protein NameCarbohydrate sulfotransferase 9
Other NameCHST9; / Carbohydrate sulfotransferase 9; / GalNAc-4-O-sulfotransferase 2; / GalNAc-4-ST2; / GalNAc4ST-2; / N-acetylgalactosamine-4-O-sulfotransferase 2
SpeciesHuman
Gene ID83539
UniprotQ7L1S5,
Species.1Mouse
Gene ID.171367
Uniprot.1Q76EC5
Species.2
Gene ID.2
Uniprot.2
Cellular Localization[Isoform 1]: Golgi apparatus membrane; Single-pass type II membrane protein .; [Isoform 2]: Secreted .
Tissue ExpressionHighly expressed in trachea. Also expressed in fetal lung, adult pancreas, testis and salivary gland. Expressed at low level in pituitary gland, apex of the heart, adult lung, prostate and mammary gland. Weakly or not expressed in heart, liver and spinal cord.
Signaling_pathway
Research Areas>>Various types of N-glycan biosynthesis; / >>Metabolic pathways
FunctionCaution:It is uncertain whether Met-1 or Met-8 is the initiator.,Function:Catalyzes the transfer of sulfate to position 4 of non-reducing N-acetylgalactosamine (GalNAc) residues in both N-glycans and O-glycans. Participates in biosynthesis of glycoprotein hormones lutropin and thyrotropin, by mediating sulfation of their carbohydrate structures. Has a higher activity toward carbonic anhydrase VI than toward lutropin. Only active against terminal GalNAcbeta1,GalNAcbeta. Isoform 2, but not isoform 1, is active toward chondroitin.,similarity:Belongs to the sulfotransferase 2 family.,tissue specificity:Highly expressed in trachea. Also expressed in fetal lung, adult pancreas, testis and salivary gland. Expressed at low level in pituitary gland, apex of the heart, adult lung, prostate and mammary gland. Weakly or not expressed in heart, liver and spinal cord.,
Please login to post questions
Back to Top
Product has been added to your cart