SKU: WP6376 Categories: ,

Cingulin rabbit pAb

Price range: $268.00 through $328.00

SKU: WP6376-100
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Product details

Background:

Specifications

Size50μL/100μL
TargetCGN
ReactivityHuman
ApplicationsWB
MW(Calculated)132kD
MW(Observed)
Host SpeciesRabbit
IsotypeIgG
Conjugate/ModificationUnmodified
Recommended Dilution RatioWB 1:500-2000
FormulationLiquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
PurificationThe antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Storage-15°C to -25°C/1 year(Do not lower than -25°C)
Concentration1 mg/ml
ClonalityPolyclonal
Clone Number
ImmunogenSynthesized peptide derived from human Cingulin
SpecificityThis antibody detects endogenous levels of Cingulin at Human
Gene NameCGN KIAA1319
Protein NameCingulin
Other Name
SpeciesHuman
Gene ID57530
UniprotQ9P2M7,
Species.1Mouse
Gene ID.1
Uniprot.1P59242
Species.2
Gene ID.2
Uniprot.2
Cellular LocalizationCell junction, tight junction . Localizes to the apical junction complex composed of tight and adherens junctions (By similarity). Colocalizes with SPEF1 at sites of cell-cell contact in intestinal epithelial cells (PubMed:12023291). .
Tissue ExpressionLocalized on the cytoplasmic face of tight junctions of polarized epithelia and some endothelia. Expressed in pancreas, kidney, liver and lung, but not in skeletal muscle, placenta, brain or heart.
Signaling_pathwayCellular Processes >> Cellular community - eukaryotes >> Tight junction
Research Areas
FunctionProbably plays a role in the formation and regulation of the tight junction (TJ) paracellular permeability barrier.
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