Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Purification
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Storage
-15°C to -25°C/1 year(Do not lower than -25°C)
Concentration
1 mg/ml
Clonality
Polyclonal
Clone Number
Immunogen
Synthesized peptide derived from human Cingulin
Specificity
This antibody detects endogenous levels of Cingulin at Human
Gene Name
CGN KIAA1319
Protein Name
Cingulin
Other Name
Species
Human
Gene ID
57530
Uniprot
Q9P2M7,
Species.1
Mouse
Gene ID.1
Uniprot.1
P59242
Species.2
Gene ID.2
Uniprot.2
Cellular Localization
Cell junction, tight junction . Localizes to the apical junction complex composed of tight and adherens junctions (By similarity). Colocalizes with SPEF1 at sites of cell-cell contact in intestinal epithelial cells (PubMed:12023291). .
Tissue Expression
Localized on the cytoplasmic face of tight junctions of polarized epithelia and some endothelia. Expressed in pancreas, kidney, liver and lung, but not in skeletal muscle, placenta, brain or heart.
Signaling_pathway
Cellular Processes >> Cellular community - eukaryotes >> Tight junction
Research Areas
Function
Probably plays a role in the formation and regulation of the tight junction (TJ) paracellular permeability barrier.