CTDSP1 Polyclonal Antibody
Ucallm_WP11830-50
Price range: $268.00 through $328.00
Product details
Background:
CTD small phosphatase 1(CTDSP1) Homo sapiens This gene encodes a member of the small C-terminal domain phosphatase (SCP) family of nuclear phosphatases. These proteins play a role in transcriptional regulation through specific dephosphorylation of phosphoserine 5 within tandem heptapeptide repeats of the C-terminal domain of RNA polymerase II. The encoded protein plays a role in neuronal gene silencing in non-neuronal cells, and may also inhibit osteoblast differentiation. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. [provided by RefSeq, Oct 2011],
Specifications
| Size | 50μL/100μL |
| Target | CTDSP1 |
| Reactivity | Human, Mouse, Rat |
| Applications | WB, IHC, IF, ELISA |
| MW(Calculated) | |
| MW(Observed) | 30kD |
| Host Species | Rabbit |
| Isotype | IgG |
| Conjugate/Modification | Unmodified |
| Recommended Dilution Ratio | WB 1:500-1:2000; IHC 1:100-1:300; ELISA 1:40000; IF 1:50-200 / Note: For IHC, we suggest antigen retrieval with TE buffer pH 9.0 (Cat#WT1004) |
| Formulation | Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide. |
| Purification | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Storage | -15°C to -25°C/1 year(Do not lower than -25°C) |
| Concentration | 1 mg/ml |
| Clonality | Polyclonal |
| Clone Number | |
| Immunogen | The antiserum was produced against synthesized peptide derived from human CTDSP1. AA range:1-50 |
| Specificity | CTDSP1 Polyclonal Antibody detects endogenous levels of CTDSP1 protein. |
| Gene Name | CTDSP1 |
| Protein Name | Carboxy-terminal domain RNA polymerase II polypeptide A small phosphatase 1 |
| Other Name | CTDSP1; / NIF3; / NLIIF; / SCP1; / Carboxy-terminal domain RNA polymerase II polypeptide A small phosphatase 1; / Nuclear LIM interactor-interacting factor 3; / NLI-IF; / NLI-interacting factor 3; / Small C-terminal domain phosphatase 1; / SCP1; / Small CTD ph |
| Species | Human |
| Gene ID | 58190 |
| Uniprot | Q9GZU7, |
| Species.1 | Mouse |
| Gene ID.1 | 227292 |
| Uniprot.1 | P58466 |
| Species.2 | |
| Gene ID.2 | |
| Uniprot.2 | |
| Cellular Localization | Nucleus . Colocalizes with RNA polymerase II. |
| Tissue Expression | Expression is restricted to non-neuronal tissues. Highest expression in skeletal muscle, spleen, lung and placenta. |
| Signaling_pathway | |
| Research Areas | |
| Function | Catalytic activity:A phosphoprotein + H(2)O = a protein + phosphate.,similarity:Contains 1 FCP1 homology domain.,subunit:May interact with LDB1 .,tissue specificity:Ubiquitously expressed, with highest expression in spleen, lung and placenta., |
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