DNASE2 rabbit pAb
Ucallm_WP7237-50
Price range: $268.00 through $328.00
Product details
Background:
Specifications
| Size | 50μL/100μL |
| Target | DNASE2 |
| Reactivity | Human, Mouse, Rat |
| Applications | WB |
| MW(Calculated) | 40kD |
| MW(Observed) | |
| Host Species | Rabbit |
| Isotype | IgG |
| Conjugate/Modification | Unmodified |
| Recommended Dilution Ratio | WB 1:500-2000 |
| Formulation | Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide. |
| Purification | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Storage | -15°C to -25°C/1 year(Do not lower than -25°C) |
| Concentration | 1 mg/ml |
| Clonality | Polyclonal |
| Clone Number | |
| Immunogen | Synthesized peptide derived from human DNASE2 |
| Specificity | This antibody detects endogenous levels of DNASE2 at Human, Mouse,Rat |
| Gene Name | DNASE2 DNASE2A DNL2 |
| Protein Name | Deoxyribonuclease-2-alpha (Acid DNase) (Deoxyribonuclease II alpha) (DNase II alpha) (Lysosomal DNase II) (R31240_2) |
| Other Name | |
| Species | Human |
| Gene ID | 1777 |
| Uniprot | O00115, |
| Species.1 | Mouse |
| Gene ID.1 | 13423 |
| Uniprot.1 | P56542, |
| Species.2 | Rat |
| Gene ID.2 | 171575 |
| Uniprot.2 | Q9QZK8 |
| Cellular Localization | Lysosome. |
| Tissue Expression | |
| Signaling_pathway | Cellular Processes >> Transport and catabolism >> Lysosome;Organismal Systems >> Immune system >> Cytosolic DNA-sensing pathway |
| Research Areas | |
| Function | Hydrolyzes DNA under acidic conditions with a preference for double-stranded DNA. Plays a major role in the degradation of nuclear DNA in cellular apoptosis during development. Necessary for proper fetal development and for definitive erythropoiesis in fetal liver, where it degrades nuclear DNA expelled from erythroid precursor cells. |
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