SKU: WP1070 Categories: ,

DPOA2 Polyclonal Antibody

Price range: $268.00 through $328.00

SKU: WP1070-100
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Product details

Background:

domain:The N-terminal 240 amino acids are sufficient to mediate complex formation., function:May play an essential role at the early stage of chromosomal DNA replication by coupling the polymerase alpha/primase complex to the cellular replication machinery., PTM:Phosphorylated in a cell cycle-dependent manner, in G2/M phase., similarity:Belongs to the DNA polymerase alpha subunit B family., subunit:DNA polymerase alpha:primase is a four subunit enzyme complex, which is assembled throughout the cell cycle, and consists of the two DNA polymerase subunits A and B, and the DNA primase large and small subunits. Subunit B binds to subunit A.,

Specifications

Size50μL/100μL
TargetDPOA2
ReactivityHuman, Mouse, Rat
ApplicationsWB, ELISA
MW(Calculated)
MW(Observed)65kD
Host SpeciesRabbit
IsotypeIgG
Conjugate/ModificationUnmodified
Recommended Dilution RatioWB 1:500-2000; ELISA 1:5000-20000
FormulationLiquid in PBS containing 50% glycerol,0.5% BSA and 0.02% sodium azide.
PurificationThe antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Storage-15°C to -25°C/1 year(Do not lower than -25°C)
Concentration1 mg/ml
ClonalityPolyclonal
Clone Number
ImmunogenSynthesized peptide derived from part region of human protein
SpecificityDPOA2 Polyclonal Antibody detects endogenous levels of protein.
Gene NamePOLA2
Protein NameDNA polymerase alpha subunit B (DNA polymerase alpha 70 kDa subunit)
Other Name
SpeciesHuman
Gene ID23649
UniprotQ14181,
Species.1Mouse
Gene ID.1
Uniprot.1P33611,
Species.2Rat
Gene ID.2
Uniprot.2O89043
Cellular LocalizationNucleus.
Tissue ExpressionCervix epithelium,Epithelium,Lung,
Signaling_pathway
Research Areas>>DNA replication
FunctionDomain:The N-terminal 240 amino acids are sufficient to mediate complex formation.,Function:May play an essential role at the early stage of chromosomal DNA replication by coupling the polymerase alpha/primase complex to the cellular replication machinery.,PTM:Phosphorylated in a cell cycle-dependent manner, in G2/M phase.,similarity:Belongs to the DNA polymerase alpha subunit B family.,subunit:DNA polymerase alpha:primase is a four subunit enzyme complex, which is assembled throughout the cell cycle, and consists of the two DNA polymerase subunits A and B, and the DNA primase large and small subunits. Subunit B binds to subunit A.,
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