SKU: WP8417 Categories: ,

DRAP1 rabbit pAb

Price range: $268.00 through $328.00

SKU: WP8417-100
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Product details

Background:

Specifications

Size50μL/100μL
TargetDRAP1
ReactivityHuman, Mouse, Rat
ApplicationsWB
MW(Calculated)23kD
MW(Observed)
Host SpeciesRabbit
IsotypeIgG
Conjugate/ModificationUnmodified
Recommended Dilution RatioWB 1:500-2000
FormulationLiquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
PurificationThe antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Storage-15°C to -25°C/1 year(Do not lower than -25°C)
Concentration1 mg/ml
ClonalityPolyclonal
Clone Number
ImmunogenSynthesized peptide derived from human DRAP1
SpecificityThis antibody detects endogenous levels of DRAP1 at Human, Mouse,Rat
Gene NameDRAP1
Protein NameDr1-associated corepressor (Dr1-associated protein 1) (Negative co-factor 2-alpha) (NC2-alpha)
Other Name
SpeciesHuman
Gene ID10589
UniprotQ14919,
Species.1Mouse
Gene ID.166556
Uniprot.1Q9D6N5,
Species.2Rat
Gene ID.2293674
Uniprot.2A0JPP1
Cellular LocalizationNucleus .
Tissue ExpressionUbiquitous. Highly expressed in adult testis, heart, skeletal muscle, pancreas and brain, and in fetal brain, liver and kidney.
Signaling_pathway
Research Areas
FunctionThe association of the DR1/DRAP1 heterodimer with TBP results in a functional repression of both activated and basal transcription of class II genes. This interaction precludes the formation of a transcription-competent complex by inhibiting the association of TFIIA and/or TFIIB with TBP. Can bind to DNA on its own.
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