Price range: $268.00 through $328.00
Background:
This gene, which is upregulated in human umbilical vein endothelial cells, encodes a G protein-coupled receptor. Variations in this gene can affect a person's stature. Multiple transcript variants encoding different proteins have been found for this gene. [provided by RefSeq, Mar 2009],
| Size | 50μL/100μL |
| Target | GPR126 |
| Reactivity | Human, Mouse |
| Applications | WB, IF, ELISA |
| MW(Calculated) | |
| MW(Observed) | 140kD |
| Host Species | Rabbit |
| Isotype | IgG |
| Conjugate/Modification | Unmodified |
| Recommended Dilution Ratio | WB 1:500-1:2000; IF 1:200-1:1000; ELISA 1:20000; Not yet tested in other applications. |
| Formulation | Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide. |
| Purification | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Storage | -15°C to -25°C/1 year(Do not lower than -25°C) |
| Concentration | 1 mg/ml |
| Clonality | Polyclonal |
| Clone Number | |
| Immunogen | The antiserum was produced against synthesized peptide derived from human GPR126. AA range:1091-1140 |
| Specificity | DREG Polyclonal Antibody detects endogenous levels of DREG protein. |
| Gene Name | GPR126 |
| Protein Name | G-protein coupled receptor 126 |
| Other Name | GPR126; / DREG; / VIGR; / G-protein coupled receptor 126; / Developmentally regulated G-protein-coupled receptor; / Vascular inducible G protein-coupled receptor |
| Species | Human |
| Gene ID | 57211 |
| Uniprot | Q86SQ4, |
| Species.1 | Mouse |
| Gene ID.1 | 215798 |
| Uniprot.1 | Q6F3F9 |
| Species.2 | |
| Gene ID.2 | |
| Uniprot.2 | |
| Cellular Localization | Cell membrane; Multi-pass membrane protein . Detected on the cell surface of activated but not resting umbilical vein. . |
| Tissue Expression | Expressed in placenta and to a lower extent in pancreas and liver. Detected in aortic endothelial cells but not in skin microvascular endothelial cells. |
| Signaling_pathway | |
| Research Areas | |
| Function | Function:Orphan receptor.,polymorphism:Genetic variations in GPR126 influences stature as a quantitative trait (STQTL) [MIM:606255]. Adult height is an easily observable and highly heritable complex continuous trait. Because of this, it is a model trait for studying genetic influence on quantitative traits.,similarity:Belongs to the G-protein coupled receptor 2 family. LN-TM7 subfamily.,similarity:Contains 1 CUB domain.,similarity:Contains 1 GPS domain.,similarity:Contains 1 pentaxin domain., |
