Dynein LC 2B Polyclonal Antibody
Product details
Background:
function:May be involved in assembly and motor function of dynein, which plays a central role in cell division and intracellular transport., miscellaneous:Expression is significantly down-regulated in hepatocellular carcinoma (HCC) patients., similarity:Belongs to the GAMAD family., tissue specificity:High expression in heart, brain, placenta, skeletal muscle, prostate and small intestine; moderate in kidney, pancreas, spleen, testis, ovary and colon; low in lung, liver, thymus and leukocyte.,
Specifications
| Size | 50μL/100μL |
| Target | Dynein LC 2B |
| Reactivity | Human, Mouse |
| Applications | IHC, IF, ELISA |
| MW(Calculated) | 11kD |
| MW(Observed) | |
| Host Species | Rabbit |
| Isotype | IgG |
| Conjugate/Modification | Unmodified |
| Recommended Dilution Ratio | IHC 1:100-1:300; ELISA 1:10000; IF 1:50-200 / Note: For IHC, we suggest antigen retrieval with TE buffer pH 9.0 (Cat#WT1004) |
| Formulation | Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide. |
| Purification | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Storage | -15°C to -25°C/1 year(Do not lower than -25°C) |
| Concentration | 1 mg/ml |
| Clonality | Polyclonal |
| Clone Number | |
| Immunogen | The antiserum was produced against synthesized peptide derived from human DYNLRB2. AA range:21-70 |
| Specificity | Dynein LC 2B Polyclonal Antibody detects endogenous levels of Dynein LC 2B protein. |
| Gene Name | DYNLRB2 |
| Protein Name | Dynein light chain roadblock-type 2 |
| Other Name | DYNLRB2; / DNCL2B; / DNLC2B; / ROBLD2; / Dynein light chain roadblock-type 2; / Dynein light chain 2B; / cytoplasmic; / Roadblock domain-containing protein 2 |
| Species | Human |
| Gene ID | 83657 |
| Uniprot | Q8TF09, |
| Species.1 | Mouse |
| Gene ID.1 | 75465 |
| Uniprot.1 | Q9DAJ5 |
| Species.2 | |
| Gene ID.2 | |
| Uniprot.2 | |
| Cellular Localization | Cytoplasm, cytoskeleton. |
| Tissue Expression | High expression in heart, brain, placenta, skeletal muscle, prostate and small intestine; moderate in kidney, pancreas, spleen, testis, ovary and colon; low in lung, liver, thymus and leukocyte. |
| Signaling_pathway | |
| Research Areas | >>Salmonella infection |
| Function | Function:May be involved in assembly and motor function of dynein, which plays a central role in cell division and intracellular transport.,miscellaneous:Expression is significantly down-regulated in hepatocellular carcinoma (HCC) patients.,similarity:Belongs to the GAMAD family.,tissue specificity:High expression in heart, brain, placenta, skeletal muscle, prostate and small intestine; moderate in kidney, pancreas, spleen, testis, ovary and colon; low in lung, liver, thymus and leukocyte., |
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