EAA4 rabbit pAb
Ucallm_WP3526-50
Price range: $268.00 through $328.00
Product details
Background:
Specifications
| Size | 50μL/100μL |
| Target | EAA4 |
| Reactivity | Human, Mouse, Rat |
| Applications | WB |
| MW(Calculated) | |
| MW(Observed) | 60kD |
| Host Species | Rabbit |
| Isotype | IgG |
| Conjugate/Modification | Unmodified |
| Recommended Dilution Ratio | WB 1:500-2000 |
| Formulation | Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide. |
| Purification | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Storage | -15°C to -25°C/1 year(Do not lower than -25°C) |
| Concentration | 1 mg/ml |
| Clonality | Polyclonal |
| Clone Number | |
| Immunogen | Synthesized peptide derived from human EAA4 AA range: 320-370 |
| Specificity | This antibody detects endogenous levels of EAA4 at Human/Mouse/Rat |
| Gene Name | SLC1A6 EAAT4 |
| Protein Name | EAA4 |
| Other Name | Excitatory amino acid transporter 4; / Sodium-dependent glutamate/aspartate transporter; / Solute carrier family 1 member 6 |
| Species | Human |
| Gene ID | 6511 |
| Uniprot | P48664, |
| Species.1 | Mouse |
| Gene ID.1 | 20513 |
| Uniprot.1 | O35544, |
| Species.2 | Rat |
| Gene ID.2 | 84012 |
| Uniprot.2 | O35921 |
| Cellular Localization | Cell membrane; Multi-pass membrane protein . |
| Tissue Expression | Brain. Expressed densely and selectively in cell bodies of Purkinje cells. |
| Signaling_pathway | Organismal Systems >> Nervous system >> Glutamatergic synapse;Organismal Systems >> Nervous system >> Synaptic vesicle cycle;Human Diseases >> Neurodegenerative disease >> Spinocerebellar ataxia |
| Research Areas | >>Synaptic vesicle cycle; / >>Glutamatergic synapse; / >>Spinocerebellar ataxia |
| Function | Function:Transports L-glutamate and also L- and D-aspartate. Seems to act as a symport by cotransporting sodium.,similarity:Belongs to the sodium:dicarboxylate (SDF) symporter (TC 2.A.23) family.,tissue specificity:Brain. Expressed densely and selectively in cell bodies of Purkinje cells., |
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