Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Purification
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Storage
-15°C to -25°C/1 year(Do not lower than -25°C)
Concentration
1 mg/ml
Clonality
Polyclonal
Clone Number
Immunogen
Synthesized peptide derived from human EMB
Specificity
This antibody detects endogenous levels of EMB at Human, Mouse,Rat
Gene Name
EMB
Protein Name
Embigin
Other Name
Species
Human
Gene ID
133418
Uniprot
Q6PCB8,
Species.1
Mouse
Gene ID.1
13723
Uniprot.1
P21995,
Species.2
Rat
Gene ID.2
114511
Uniprot.2
O88775
Cellular Localization
Cell membrane; Single-pass type I membrane protein . Cell junction, synapse . Localizes to the neuromuscular junctions. .
Tissue Expression
Signaling_pathway
Research Areas
Function
Plays a role in the outgrowth of motoneurons and in the formation of neuromuscular junctions. Following muscle denervation, promotes nerve terminal sprouting and the formation of additional acetylcholine receptor clusters at synaptic sites without affecting terminal Schwann cell number or morphology. Delays the retraction of terminal sprouts following re-innervation of denervated endplates. May play a role in targeting the monocarboxylate transporters SLC16A1 and SLC16A7 to the cell membrane (By similarity).