SKU: WP8742 Categories: ,

EMB rabbit pAb

Price range: $268.00 through $328.00

SKU: WP8742-100
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Product details

Background:

Specifications

Size50μL/100μL
TargetEMB
ReactivityHuman, Mouse, Rat
ApplicationsWB
MW(Calculated)36kD
MW(Observed)
Host SpeciesRabbit
IsotypeIgG
Conjugate/ModificationUnmodified
Recommended Dilution RatioWB 1:500-2000
FormulationLiquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
PurificationThe antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Storage-15°C to -25°C/1 year(Do not lower than -25°C)
Concentration1 mg/ml
ClonalityPolyclonal
Clone Number
ImmunogenSynthesized peptide derived from human EMB
SpecificityThis antibody detects endogenous levels of EMB at Human, Mouse,Rat
Gene NameEMB
Protein NameEmbigin
Other Name
SpeciesHuman
Gene ID133418
UniprotQ6PCB8,
Species.1Mouse
Gene ID.113723
Uniprot.1P21995,
Species.2Rat
Gene ID.2114511
Uniprot.2O88775
Cellular LocalizationCell membrane; Single-pass type I membrane protein . Cell junction, synapse . Localizes to the neuromuscular junctions. .
Tissue Expression
Signaling_pathway
Research Areas
FunctionPlays a role in the outgrowth of motoneurons and in the formation of neuromuscular junctions. Following muscle denervation, promotes nerve terminal sprouting and the formation of additional acetylcholine receptor clusters at synaptic sites without affecting terminal Schwann cell number or morphology. Delays the retraction of terminal sprouts following re-innervation of denervated endplates. May play a role in targeting the monocarboxylate transporters SLC16A1 and SLC16A7 to the cell membrane (By similarity).
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