FAM111B Polyclonal Antibody
Ucallm_WP12269-50
Price range: $268.00 through $328.00
Product details
Background:
This gene encodes a protein with a trypsin-like cysteine/serine peptidase domain in the C-terminus. Mutations in this gene are associated with an autosomal dominant form of hereditary fibrosing poikiloderma (HFP). Affected individuals display mottled pigmentation, telangiectasia, epidermal atrophy, tendon contractures, and progressive pulmonary fibrosis. Alternative splicing results in multiple transcript variants encoding distinct isoforms. A paralog of this gene which also has a trypsin‐like peptidase domain, FAM111A, is located only 16 kb from this gene on human chromosome 11q12.1. [provided by RefSeq, Apr 2014],
Specifications
| Size | 50μL/100μL |
| Target | FAM111B |
| Reactivity | Human |
| Applications | IHC, IF, ELISA |
| MW(Calculated) | 85kD |
| MW(Observed) | |
| Host Species | Rabbit |
| Isotype | IgG |
| Conjugate/Modification | Unmodified |
| Recommended Dilution Ratio | IHC 1:100-1:200; ELISA 1:5000; IF 1:50-200 / Note: For IHC, we suggest antigen retrieval with TE buffer pH 9.0 (Cat#WT1004) |
| Formulation | Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide. |
| Purification | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Storage | -15°C to -25°C/1 year(Do not lower than -25°C) |
| Concentration | 1 mg/ml |
| Clonality | Polyclonal |
| Clone Number | |
| Immunogen | The antiserum was produced against synthesized peptide derived from human F111B. AA range:281-330 |
| Specificity | FAM111B Polyclonal Antibody detects endogenous levels of FAM111B protein. |
| Gene Name | FAM111B |
| Protein Name | Protein FAM111B |
| Other Name | FAM111B; / CANP; / Protein FAM111B; / Cancer-associated nucleoprotein |
| Species | Human |
| Gene ID | 374393 |
| Uniprot | Q6SJ93 |
| Species.1 | |
| Gene ID.1 | |
| Uniprot.1 | |
| Species.2 | |
| Gene ID.2 | |
| Uniprot.2 | |
| Cellular Localization | |
| Tissue Expression | Widely expressed. |
| Signaling_pathway | |
| Research Areas | |
| Function | sequence Caution:Contaminating sequence. Potential poly-A sequence.,similarity:Belongs to the FAM111 family., |
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