Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Purification
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Storage
-15°C to -25°C/1 year(Do not lower than -25°C)
Concentration
1 mg/ml
Clonality
Polyclonal
Clone Number
Immunogen
Synthesized peptide derived from human FBXW4
Specificity
This antibody detects endogenous levels of FBXW4 at Human, Mouse
Gene Name
FBXW4 FBW4 SHFM3
Protein Name
F-box/WD repeat-containing protein 4 (Dactylin) (F-box and WD-40 domain-containing protein 4)
Other Name
Species
Human
Gene ID
6468
Uniprot
P57775,
Species.1
Mouse
Gene ID.1
30838
Uniprot.1
Q9JMJ2
Species.2
Gene ID.2
Uniprot.2
Cellular Localization
Tissue Expression
Expressed in brain, kidney, lung and liver.
Signaling_pathway
Research Areas
Function
Probably recognizes and binds to some phosphorylated proteins and promotes their ubiquitination and degradation. Likely to be involved in key signaling pathways crucial for normal limb development. May participate in Wnt signaling.