FGGY Polyclonal Antibody
Ucallm_WP2871-50
Price range: $268.00 through $328.00
Product details
Background:
This gene encodes a protein that phosphorylates carbohydrates such as ribulose, ribitol, and L-arabinitol. Genome-wide association studies in some populations have found an association between polymorphisms in this gene and sporadic amyotrophic lateral sclerosis, but studies of other populations have not been able to replicate this association. Alternative splicing results in multiple transcript variants. [provided by RefSeq, May 2013],
Specifications
| Size | 50μL/100μL |
| Target | FGGY |
| Reactivity | Human, Mouse |
| Applications | WB, ELISA |
| MW(Calculated) | |
| MW(Observed) | 60kD |
| Host Species | Rabbit |
| Isotype | IgG |
| Conjugate/Modification | Unmodified |
| Recommended Dilution Ratio | WB 1:500-2000; ELISA 1:5000-20000 |
| Formulation | Liquid in PBS containing 50% glycerol,0.5% BSA and 0.02% sodium azide. |
| Purification | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Storage | -15°C to -25°C/1 year(Do not lower than -25°C) |
| Concentration | 1 mg/ml |
| Clonality | Polyclonal |
| Clone Number | |
| Immunogen | Synthesized peptide derived from human protein . at AA range: 491-540 |
| Specificity | FGGY Polyclonal Antibody detects endogenous levels of protein. |
| Gene Name | FGGY |
| Protein Name | FGGY carbohydrate kinase domain-containing protein (EC 2.7.1.-) |
| Other Name | |
| Species | Human |
| Gene ID | 55277 |
| Uniprot | Q96C11, |
| Species.1 | Mouse |
| Gene ID.1 | |
| Uniprot.1 | A2AJL3 |
| Species.2 | |
| Gene ID.2 | |
| Uniprot.2 | |
| Cellular Localization | cytoplasm, |
| Tissue Expression | Expressed in kidney, lung and small intestine and to a lower extent in liver and detected in cerebrospinal fluid (at protein level). |
| Signaling_pathway | |
| Research Areas | >>Pentose and glucuronate interconversions; / >>Metabolic pathways |
| Function | developmental stage:Expressed in fetal brain (at protein level).,Disease:Defects in FGGY are associated with sporadic amyotrophic lateral sclerosis (ALS) [MIM:105400]. Amyotrophic lateral sclerosis is a neurodegenerative disorder affecting upper and lower motor neurons and resulting in fatal paralysis. Sensory abnormalities are absent. Death usually occurs within 2 to 5 years. The etiology of amyotrophic lateral sclerosis is likely to be multifactorial, involving both genetic and environmental factors.,similarity:Belongs to the FGGY kinase family.,tissue specificity:Expressed in kidney, lung and small intestine and to a lower extent in liver and detected in cerebrospinal fluid (at protein level)., |
Please login to post questions
Related products
