Price range: $268.00 through $328.00
Background:
The protein encoded by this gene is a transcription factor that contains two GATA-type zinc fingers. The encoded protein is known to bind to hepatocyte nuclear factor-1alpha (HNF-1alpha), and this interaction is essential for cooperative activation of the intestinal lactase-phlorizin hydrolase promoter. In other organisms, similar proteins may be involved in the establishment of cardiac smooth muscle cell diversity. [provided by RefSeq, Jul 2008],
| Size | 50μL/100μL |
| Target | GATA-5 |
| Reactivity | Human |
| Applications | WB, ELISA |
| MW(Calculated) | 41kD |
| MW(Observed) | |
| Host Species | Mouse |
| Isotype | |
| Conjugate/Modification | Unmodified |
| Recommended Dilution Ratio | WB 1:500-1:2000; ELISA 1:10000; Not yet tested in other applications. |
| Formulation | Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide. |
| Purification | Affinity purification |
| Storage | -15°C to -25°C/1 year(Do not lower than -25°C) |
| Concentration | |
| Clonality | Monoclonal |
| Clone Number | 20E9 |
| Immunogen | Purified recombinant fragment of human GATA-5 expressed in E. Coli. |
| Specificity | GATA-5 Monoclonal Antibody detects endogenous levels of GATA-5 protein. |
| Gene Name | GATA5 |
| Protein Name | Transcription factor GATA-5 |
| Other Name | GATA5; / Transcription factor GATA-5; / GATA-binding factor 5 |
| Species | Human |
| Gene ID | 140628 |
| Uniprot | Q9BWX5 |
| Species.1 | |
| Gene ID.1 | |
| Uniprot.1 | |
| Species.2 | |
| Gene ID.2 | |
| Uniprot.2 | |
| Cellular Localization | Nucleus . |
| Tissue Expression | Uterus, |
| Signaling_pathway | |
| Research Areas | |
| Function | Function:Binds to the functionally important CEF-1 nuclear protein binding site in the cardiac-specific slow/cardiac troponin C transcriptional enhancer. May play an important role in the transcriptional program(s) that underlies smooth muscle cell diversity.,similarity:Contains 2 GATA-type zinc fingers., |
