SKU: WM1423 Categories: ,

GCDFP-15 [ABT330] mouse mAb

Price range: $268.00 through $328.00

SKU: WM1423-50
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Product details

Background:
GCDFP-15 is a single chain protein with a molecular weight of 15 kDa. It is induced by prolactin and androgen and is common in the vesicle fluid of vesicular disease. It is expressed in non neoplastic serous salivary gland acinus, bronchial serous gland, seminal vesicle and cutaneous sweat gland. GCDFP-15 is a highly specific and sensitive marker for breast and its tumors. It is used for the diagnosis and differential diagnosis of metastatic breast cancer and other parts of the primary cancer.

Specifications

Size50μL/100μL
TargetGCDFP-15
ReactivityHuman
ApplicationsIHC, WB, IF, ELISA
MW(Calculated)17kD
MW(Observed)15kD
Host SpeciesMouse
IsotypeIgG1,Kappa
Conjugate/ModificationUnmodified
Recommended Dilution RatioIHC 1:200-1000; WB 1:500-2000; IF 1:100-500; ELISA 1:1000-5000 / Note: For IHC, we suggest antigen retrieval with TE buffer pH 9.0 (Cat#WT1004)
FormulationPBS, 50% glycerol, 0.05% Proclin 300, 0.05%BSA
PurificationRecombinant Antibody expressed in animal component-free (ACF) media, purified via Protein G affinity chromatography.
Storage-15°C to -25°C/1 year(Do not lower than -25°C)
Concentration
ClonalityMonoclonal
Clone NumberRMM330
ImmunogenSynthesized peptide derived from human Gross cystic disease fluid protein-15 (GCDFP-15) AA range: 50-146
SpecificityThe antibody can specifically recognize human GCDFP-15 protein.
Gene NamePIP GCDFP15 GPIP4
Protein NameGross cystic disease fluid protein-15 (GCDFP-15)
Other NameBRST-2; / BRST2; / GCDFP-15; / GCDGP15; / gp17; / GPIP4; / Gross cystic disease fluid protein 15; / PIP; / PIP_HUMAN; / Prolactin induced protein; / Prolactin inducible protein precursor; / Prolactin-induced protein; / Prolactin-inducible protein; / SABP; / Secretory actin binding protein; / Secretory actin-binding protein
SpeciesHuman
Gene ID5304
UniprotP12273
Species.1
Gene ID.1
Uniprot.1
Species.2
Gene ID.2
Uniprot.2
Cellular LocalizationCytoplasmic
Tissue ExpressionExpressed in pathological conditions of the mammary gland and in several exocrine tissues, such as the lacrimal, salivary, and sweat glands.
Signaling_pathway
Research Areas
Functioninduction:By prolactin and androgen; inhibited by estrogen.,similarity:Belongs to the PIP family.,subunit:Monomer. Interacts with AZGP1.,tissue specificity:Expressed in pathological conditions of the mammary gland and in several exocrine tissues, such as the lacrimal, salivary, and sweat glands.,
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