GKN1 rabbit pAb
Product details
Background:
The protein encoded by this gene is found to be down-regulated in human gastric cancer tissue as compared to normal gastric mucosa. [provided by RefSeq, Jul 2008],
Specifications
| Size | 50μL/100μL |
| Target | GKN1 |
| Reactivity | Human, Mouse |
| Applications | WB |
| MW(Calculated) | 22kD |
| MW(Observed) | |
| Host Species | Rabbit |
| Isotype | IgG |
| Conjugate/Modification | Unmodified |
| Recommended Dilution Ratio | WB 1:500-2000 |
| Formulation | Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide. |
| Purification | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Storage | -15°C to -25°C/1 year(Do not lower than -25°C) |
| Concentration | 1 mg/ml |
| Clonality | Polyclonal |
| Clone Number | |
| Immunogen | Synthesized peptide derived from human GKN1 AA range: 47-97 |
| Specificity | This antibody detects endogenous levels of GKN1 at Human/Mouse |
| Gene Name | GKN1 AMP18 CA11 UNQ489/PRO1005 |
| Protein Name | GKN1 |
| Other Name | |
| Species | Human |
| Gene ID | 56287 |
| Uniprot | Q9NS71, |
| Species.1 | Mouse |
| Gene ID.1 | 66283 |
| Uniprot.1 | Q9CR36 |
| Species.2 | |
| Gene ID.2 | |
| Uniprot.2 | |
| Cellular Localization | Secreted . Cytoplasmic granule . Golgi apparatus . Shows abundant granular cytoplasmic staining, with perinuclear accentuation suggestive of the Golgi apparatus. . |
| Tissue Expression | Expressed in stomach (at protein level). No expression is detected in cancer tissue or gastric cancer cell lines. |
| Signaling_pathway | |
| Research Areas | |
| Function | Caution:It is uncertain whether Met-1 or Met-15 is the initiator.,Function:Has mitogenic activity and may be involved in maintaining the integrity of the gastric mucosal epithelium.,similarity:Belongs to the gastrokine family.,similarity:Contains 1 BRICHOS domain.,tissue specificity:Expressed in stomach. No expression is detected in cancer tissue or gastric cancer cell lines., |
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