Name: hCG α [ABT-HCG] mouse mAb
SKU: WM1525
Price: 268 USD
Availability: InStock

hCG α [ABT-HCG] mouse mAb

Ucallm_WM1525-50

Price range: $268.00 through $328.00

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50μl

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SKU: WM1525-50

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Product details

Background:
The four human glycoprotein hormones chorionic gonadotropin (CG), luteinizing hormone (LH), follicle stimulating hormone (FSH), and thyroid stimulating hormone (TSH) are dimers consisting of alpha and beta subunits that are associated noncovalently. The alpha subunits of these hormones are identical, however, their beta chains are unique and confer biological specificity. The protein encoded by this gene is the alpha subunit and belongs to the glycoprotein hormones alpha chain family. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Nov 2011],

Specifications

Size	50μL/100μL
Target	hCG
Reactivity	Human
Applications	IHC, WB, IF, ELISA
MW(Calculated)	13kD
MW(Observed)	13kD
Host Species	Mouse
Isotype	IgG2a,Kappa
Conjugate/Modification	Unmodified
Recommended Dilution Ratio	IHC 1:200-1000; WB 1:500-2000; IF 1:100-500; ELISA 1:1000-5000 / Note: For IHC, we suggest antigen retrieval with TE buffer pH 9.0 (Cat#WT1004)
Formulation	PBS, 50% glycerol, 0.05% Proclin 300, 0.05%BSA
Purification	Recombinant Antibody expressed in animal component-free (ACF) media, purified via Protein G affinity chromatography.
Storage	-15°C to -25°C/1 year(Do not lower than -25°C)
Concentration
Clonality	Monoclonal
Clone Number	RMM-HCG
Immunogen	Synthesized peptide derived from human hCG AA range: 25-100
Specificity	The antibody can specifically recognize α subunits of human CG, LH, FSH and TSH proteins. In western blotting of Hela cell lysate, the antibody can label a 18 kDa band.
Gene Name	CGA
Protein Name	Glycoprotein hormones alpha chain (Anterior pituitary glycoprotein hormones common subunit alpha) (Choriogonadotropin alpha chain) (Chorionic gonadotrophin subunit alpha) (CG-alpha) (Follicle-stimulating hormone alpha chain) (FSH-alpha) (Follitropin alpha chain) (Luteinizing hormone alpha chain) (LSH-alpha) (Lutropin alpha chain) (Thyroid-stimulating hormone alpha chain) (TSH-alpha) (Thyrotropin alpha chain)
Other Name
Species	Human
Gene ID	1081
Uniprot	P01215
Species.1
Gene ID.1
Uniprot.1
Species.2
Gene ID.2
Uniprot.2
Cellular Localization	Cytoplasmic
Tissue Expression	Pituitary,Placenta,
Signaling_pathway	Organismal Systems >> Endocrine system >> GnRH signaling pathway;Organismal Systems >> Endocrine system >> Prolactin signaling pathway;Human Diseases >> Immune disease >> Autoimmune thyroid disease;Environmental Information Processing >> Signal transduction >> cAMP signaling pathway
Research Areas	>>cAMP signaling pathway; / >>Neuroactive ligand-receptor interaction; / >>GnRH signaling pathway; / >>Ovarian steroidogenesis; / >>Prolactin signaling pathway; / >>Thyroid hormone synthesis; / >>Regulation of lipolysis in adipocytes; / >>GnRH secretion; / >>Autoimmune thyroid disease
Function	online information:Proteic grace - Issue 77 of December 2006,similarity:Belongs to the glycoprotein hormones subunit alpha family.,subunit:Heterodimer of a common alpha chain and a unique beta chain which confers biological specificity to thyrotropin, lutropin, follitropin and gonadotropin.,

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hCG α [ABT-HCG] mouse mAb

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hCG α [ABT-HCG] mouse mAb

Product details

Specifications

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