HLCS rabbit pAb
Product details
Background:
Specifications
| Size | 50μL/100μL |
| Target | HLCS |
| Reactivity | Human, Mouse |
| Applications | WB |
| MW(Calculated) | 80kD |
| MW(Observed) | |
| Host Species | Rabbit |
| Isotype | IgG |
| Conjugate/Modification | Unmodified |
| Recommended Dilution Ratio | WB 1:500-2000 |
| Formulation | Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide. |
| Purification | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Storage | -15°C to -25°C/1 year(Do not lower than -25°C) |
| Concentration | 1 mg/ml |
| Clonality | Polyclonal |
| Clone Number | |
| Immunogen | Synthesized peptide derived from human HLCS |
| Specificity | This antibody detects endogenous levels of HLCS at Human, Mouse |
| Gene Name | HLCS |
| Protein Name | Biotin--protein ligase (Biotin apo-protein ligase) [Includes: Biotin--[methylmalonyl-CoA-carboxytransferase] ligase (Holocarboxylase synthetase) (HCS); Biotin--[methylcrotonoyl-CoA-carboxylase] ligase (EC 6.3.4.11); Biotin--[acetyl-CoA-carboxylase] ligase (EC 6.3.4.15)] |
| Other Name | |
| Species | Human |
| Gene ID | 3141 |
| Uniprot | P50747, |
| Species.1 | Mouse |
| Gene ID.1 | 110948 |
| Uniprot.1 | Q920N2 |
| Species.2 | |
| Gene ID.2 | |
| Uniprot.2 | |
| Cellular Localization | Cytoplasm . Mitochondrion . |
| Tissue Expression | Widely expressed (PubMed:7842009, PubMed:7753853). Mostly expressed in muscle, placenta and to a lower extent in the brain, kidney, pancreas, liver and lung (PubMed:7842009). |
| Signaling_pathway | |
| Research Areas | |
| Function | Biotin--protein ligase catalyzing the biotinylation of the 4 biotin-dependent carboxylases acetyl-CoA-carboxylase, pyruvate carboxylase, propionyl-CoA carboxylase, and methylcrotonyl-CoA carboxylase. |
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