HSP A9 Polyclonal Antibody
Ucallm_WP12756-50
Price range: $268.00 through $328.00
Product details
Background:
This gene encodes a member of the heat shock protein 70 gene family. The encoded protein is primarily localized to the mitochondria but is also found in the endoplasmic reticulum, plasma membrane and cytoplasmic vesicles. This protein is a heat-shock cognate protein. This protein plays a role in cell proliferation, stress response and maintenance of the mitochondria. A pseudogene of this gene is found on chromosome 2.[provided by RefSeq, May 2010],
Specifications
| Size | 50μL/100μL |
| Target | HSP A9 |
| Reactivity | Human, Mouse, Rat, Monkey |
| Applications | WB, IHC, IF, ELISA |
| MW(Calculated) | |
| MW(Observed) | 75kD |
| Host Species | Rabbit |
| Isotype | IgG |
| Conjugate/Modification | Unmodified |
| Recommended Dilution Ratio | WB 1:500-1:2000; IHC 1:100-1:300; IF 1:200-1:1000; ELISA 1:40000; Not yet tested in other applications. / Note: For IHC, we suggest antigen retrieval with TE buffer pH 9.0 (Cat#WT1004) |
| Formulation | Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide. |
| Purification | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Storage | -15°C to -25°C/1 year(Do not lower than -25°C) |
| Concentration | 1 mg/ml |
| Clonality | Polyclonal |
| Clone Number | |
| Immunogen | The antiserum was produced against synthesized peptide derived from human GRP75. AA range:630-679 |
| Specificity | HSP A9 Polyclonal Antibody detects endogenous levels of HSP A9 protein. |
| Gene Name | HSPA9 |
| Protein Name | Stress-70 protein mitochondrial |
| Other Name | HSPA9; / GRP75; / HSPA9B; / Stress-70 protein; / mitochondrial; / 75 kDa glucose-regulated protein; / GRP-75; / Heat shock 70 kDa protein 9; / Mortalin; / MOT; / Peptide-binding protein 74; / PBP74 |
| Species | Human |
| Gene ID | 3313 |
| Uniprot | P38646;Q8N1C8, |
| Species.1 | Mouse |
| Gene ID.1 | 15526, |
| Uniprot.1 | |
| Species.2 | Rat |
| Gene ID.2 | 291671 |
| Uniprot.2 | P48721 |
| Cellular Localization | Mitochondrion . Nucleus, nucleolus . |
| Tissue Expression | B-cell,Brain,Cajal-Retzius cell,Colon carcinoma,Fetal brain |
| Signaling_pathway | Genetic Information Processing >> Folding, sorting and degradation >> RNA degradation |
| Research Areas | >>RNA degradation; / >>Tuberculosis |
| Function | Function:Implicated in the control of cell proliferation and cellular aging. May also act as a chaperone.,PTM:Phosphorylated upon DNA damage, probably by ATM or ATR.,similarity:Belongs to the heat shock protein 70 family.,subunit:Interacts with FXN., |
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