HSPBAP1 Polyclonal Antibody
Ucallm_WP15225-50
Price range: $268.00 through $328.00
Product details
Background:
This gene encodes a protein that binds to one of the small heat shock proteins, specifically hsp27. Hsp27 is involved with cell growth and differentiation. This encoded protein was found to be abnormally expressed in patients with intractable epilepsy, although how brain function is affected remains unknown. [provided by RefSeq, Sep 2011],
Specifications
| Size | 50μL/100μL |
| Target | HSPBAP1 |
| Reactivity | Human, Mouse, Rat |
| Applications | WB, IHC, IF, ELISA |
| MW(Calculated) | |
| MW(Observed) | 55kD |
| Host Species | Rabbit |
| Isotype | IgG |
| Conjugate/Modification | Unmodified |
| Recommended Dilution Ratio | WB 1:500-1:2000; IHC: 1:100-300; ELISA 1:20000; IF 1:50-200 / Note: For IHC, we suggest antigen retrieval with TE buffer pH 9.0 (Cat#WT1004) |
| Formulation | Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide. |
| Purification | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Storage | -15°C to -25°C/1 year(Do not lower than -25°C) |
| Concentration | 1 mg/ml |
| Clonality | Polyclonal |
| Clone Number | |
| Immunogen | The antiserum was produced against synthesized peptide derived from the Internal region of human HSPBAP1. AA range:321-370 |
| Specificity | HSPBAP1 Polyclonal Antibody detects endogenous levels of HSPBAP1 protein. |
| Gene Name | HSPBAP1 |
| Protein Name | HSPB1-associated protein 1 |
| Other Name | HSPBAP1; / PASS1; / HSPB1-associated protein 1; / 27 kDa heat shock protein-associated protein 1; / Protein associated with small stress protein 1 |
| Species | Human |
| Gene ID | 79663 |
| Uniprot | Q96EW2, |
| Species.1 | Mouse |
| Gene ID.1 | |
| Uniprot.1 | Q8BK58 |
| Species.2 | |
| Gene ID.2 | |
| Uniprot.2 | |
| Cellular Localization | Cytoplasm . |
| Tissue Expression | Widely expressed. |
| Signaling_pathway | |
| Research Areas | |
| Function | Disease:A chromosomal aberration involving HSPBAP1 is found in familial renal cell carcinoma 1 (RCC1) [MIM:144700]. Translocation t(2; 3)(q35; q21) with the putative pseudogene DIRC3. Produces an hybrid mRNA encoding a truncated HSPBAP1 lacking the first 36 amino acids.,Function:May play a role in cellular stress response.,similarity:Contains 1 JmjC domain.,subunit:Interacts with CRYAB and HSPB1.,tissue specificity:Widely expressed., |
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