IARS2 Polyclonal Antibody
Ucallm_WP12772-50
Price range: $268.00 through $328.00
Product details
Background:
Aminoacyl-tRNA synthetases catalyze the aminoacylation of tRNA by their cognate amino acid. Because of their central role in linking amino acids with nucleotide triplets contained in tRNAS, aminoacyl-tRNA synthetases are thought to be among the first proteins that appeared in evolution. Two forms of isoleucine-tRNA synthetase exist, a cytoplasmic form and a mitochondrial form. This gene encodes the mitochondrial isoleucine-tRNA synthetase which belongs to the class-I aminoacyl-tRNA synthetase family. [provided by RefSeq, Dec 2014],
Specifications
| Size | 50μL/100μL |
| Target | IARS2 |
| Reactivity | Human, Mouse, Monkey |
| Applications | WB, IHC, IF, ELISA |
| MW(Calculated) | |
| MW(Observed) | 114kD |
| Host Species | Rabbit |
| Isotype | IgG |
| Conjugate/Modification | Unmodified |
| Recommended Dilution Ratio | WB 1:500-1:2000; IHC 1:100-1:300; IF 1:200-1:1000; ELISA 1:20000; Not yet tested in other applications. / Note: For IHC, we suggest antigen retrieval with TE buffer pH 9.0 (Cat#WT1004) |
| Formulation | Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide. |
| Purification | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Storage | -15°C to -25°C/1 year(Do not lower than -25°C) |
| Concentration | 1 mg/ml |
| Clonality | Polyclonal |
| Clone Number | |
| Immunogen | The antiserum was produced against synthesized peptide derived from human IARS2. AA range:71-120 |
| Specificity | IARS2 Polyclonal Antibody detects endogenous levels of IARS2 protein. |
| Gene Name | IARS2 |
| Protein Name | Isoleucine--tRNA ligase mitochondrial |
| Other Name | IARS2; / Isoleucine--tRNA ligase; / mitochondrial; / Isoleucyl-tRNA synthetase; / IleRS |
| Species | Human |
| Gene ID | 55699 |
| Uniprot | Q9NSE4, |
| Species.1 | Mouse |
| Gene ID.1 | 381314 |
| Uniprot.1 | Q8BIJ6 |
| Species.2 | |
| Gene ID.2 | |
| Uniprot.2 | |
| Cellular Localization | Mitochondrion matrix . |
| Tissue Expression | Brain,Epithelium,Liver,Placenta,Skin, |
| Signaling_pathway | |
| Research Areas | >>Aminoacyl-tRNA biosynthesis |
| Function | Catalytic activity:ATP + L-isoleucine + tRNA(Ile) = AMP + diphosphate + L-isoleucyl-tRNA(Ile).,similarity:Belongs to the class-I aminoacyl-tRNA synthetase family., |
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