IBPL1 Polyclonal Antibody
Product details
Background:
function:IGF-binding proteins prolong the half-life of IGFs and have been shown to either inhibit or stimulate the growth promoting effects of the IGFs in cell culture. They alter the interaction of IGFs with their cell surface receptors (By similarity). May be a putative tumor suppressor protein., induction:Down-regulated in multiple tumors., similarity:Contains 1 Ig-like C2-type (immunoglobulin-like) domain., similarity:Contains 1 IGFBP N-terminal domain., similarity:Contains 1 Kazal-like domain., tissue specificity:Expressed at the highest level in both brain and testis, with lower levels in the prostate, bladder and lung.,
Specifications
| Size | 50μL/100μL |
| Target | IBPL1 |
| Reactivity | Human, Mouse |
| Applications | WB, ELISA |
| MW(Calculated) | |
| MW(Observed) | 30kD |
| Host Species | Rabbit |
| Isotype | IgG |
| Conjugate/Modification | Unmodified |
| Recommended Dilution Ratio | WB 1:500-2000; ELISA 1:5000-20000 |
| Formulation | Liquid in PBS containing 50% glycerol,0.5% BSA and 0.02% sodium azide. |
| Purification | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Storage | -15°C to -25°C/1 year(Do not lower than -25°C) |
| Concentration | 1 mg/ml |
| Clonality | Polyclonal |
| Clone Number | |
| Immunogen | Synthesized peptide derived from part region of human protein |
| Specificity | IBPL1 Polyclonal Antibody detects endogenous levels of protein. |
| Gene Name | IGFBPL1 IGFBPRP4 |
| Protein Name | Insulin-like growth factor-binding protein-like 1 (IGFBP-related protein 10) (Insulin-like growth factor-binding-related protein 4) (IGFBP-rP4) |
| Other Name | |
| Species | Human |
| Gene ID | 347252 |
| Uniprot | Q8WX77, |
| Species.1 | Mouse |
| Gene ID.1 | |
| Uniprot.1 | Q80W15 |
| Species.2 | |
| Gene ID.2 | |
| Uniprot.2 | |
| Cellular Localization | Secreted . |
| Tissue Expression | Expressed at the highest level in both brain and testis, with lower levels in the prostate, bladder and lung. |
| Signaling_pathway | |
| Research Areas | |
| Function | Function:IGF-binding proteins prolong the half-life of IGFs and have been shown to either inhibit or stimulate the growth promoting effects of the IGFs in cell culture. They alter the interaction of IGFs with their cell surface receptors (By similarity). May be a putative tumor suppressor protein.,induction:Down-regulated in multiple tumors.,similarity:Contains 1 Ig-like C2-type (immunoglobulin-like) domain.,similarity:Contains 1 IGFBP N-terminal domain.,similarity:Contains 1 Kazal-like domain.,tissue specificity:Expressed at the highest level in both brain and testis, with lower levels in the prostate, bladder and lung., |
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