SKU: WP12795 Categories: ,

IGSF4D Polyclonal Antibody

Price range: $268.00 through $328.00

SKU: WP12795-100
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Product details

Background:

cell adhesion molecule 2(CADM2) Homo sapiens This gene encodes a member of the synaptic cell adhesion molecule 1 (SynCAM) family which belongs to the immunoglobulin (Ig) superfamily. The encoded protein has three Ig-like domains and a cytosolic protein 4.1 binding site near the C-terminus. Proteins belonging to the protein 4.1 family crosslink spectrin and interact with other cytoskeletal proteins. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Feb 2012],

Specifications

Size50μL/100μL
TargetIGSF4D
ReactivityHuman, Mouse, Rat
ApplicationsWB, IHC, IF, ELISA
MW(Calculated)
MW(Observed)47kD
Host SpeciesRabbit
IsotypeIgG
Conjugate/ModificationUnmodified
Recommended Dilution RatioWB 1:500-1:2000; IHC 1:100-1:300; IF 1:200-1:1000; ELISA 1:10000; Not yet tested in other applications. / Note: For IHC, we suggest antigen retrieval with TE buffer pH 9.0 (Cat#WT1004)
FormulationLiquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
PurificationThe antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Storage-15°C to -25°C/1 year(Do not lower than -25°C)
Concentration1 mg/ml
ClonalityPolyclonal
Clone Number
ImmunogenThe antiserum was produced against synthesized peptide derived from human CADM2. AA range:131-180
SpecificityIGSF4D Polyclonal Antibody detects endogenous levels of IGSF4D protein.
Gene NameCADM2
Protein NameCell adhesion molecule 2
Other NameCADM2; / IGSF4D; / NECL3; / Cell adhesion molecule 2; / Immunoglobulin superfamily member 4D; / IgSF4D; / Nectin-like protein 3; / NECL-3; / Synaptic cell adhesion molecule 2; / SynCAM 2
SpeciesHuman
Gene ID253559
UniprotQ8N3J6,
Species.1Mouse
Gene ID.1239857
Uniprot.1Q8BLQ9,
Species.2Rat
Gene ID.2360687
Uniprot.2Q1WIM2
Cellular LocalizationCell membrane; Single-pass type I membrane protein . Cell junction, synapse . Cell projection, axon . Found in the axoplasm of myelinated axons.
Tissue ExpressionAmygdala,Brain,Stomach,
Signaling_pathway
Research Areas
Functionsimilarity:Belongs to the nectin family.,similarity:Contains 1 Ig-like V-type (immunoglobulin-like) domain.,similarity:Contains 2 Ig-like C2-type (immunoglobulin-like) domains.,
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