SKU: WP6353 Categories: ,

INTS10 rabbit pAb

Price range: $268.00 through $328.00

SKU: WP6353-100
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Product details

Background:

Specifications

Size50μL/100μL
TargetINTS10
ReactivityHuman, Mouse
ApplicationsWB
MW(Calculated)78kD
MW(Observed)
Host SpeciesRabbit
IsotypeIgG
Conjugate/ModificationUnmodified
Recommended Dilution RatioWB 1:500-2000
FormulationLiquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
PurificationThe antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Storage-15°C to -25°C/1 year(Do not lower than -25°C)
Concentration1 mg/ml
ClonalityPolyclonal
Clone Number
ImmunogenSynthesized peptide derived from human INTS10
SpecificityThis antibody detects endogenous levels of INTS10 at Human, Mouse
Gene NameINTS10 C8orf35
Protein NameIntegrator complex subunit 10 (Int10)
Other Name
SpeciesHuman
Gene ID55174
UniprotQ9NVR2,
Species.1Mouse
Gene ID.170885
Uniprot.1Q8K2A7
Species.2
Gene ID.2
Uniprot.2
Cellular LocalizationNucleus .
Tissue Expression
Signaling_pathway
Research Areas
FunctionComponent of the Integrator (INT) complex, a complex involved in the small nuclear RNAs (snRNA) U1 and U2 transcription and in their 3'-box-dependent processing. The Integrator complex is associated with the C-terminal domain (CTD) of RNA polymerase II largest subunit (POLR2A) and is recruited to the U1 and U2 snRNAs genes (Probable). May be not involved in the recruitment of cytoplasmic dynein to the nuclear envelope by different components of the INT complex .
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