Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Purification
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Storage
-15°C to -25°C/1 year(Do not lower than -25°C)
Concentration
1 mg/ml
Clonality
Polyclonal
Clone Number
Immunogen
Synthesized peptide derived from human INTS5
Specificity
This antibody detects endogenous levels of INTS5 at Human, Mouse
Gene Name
INTS5 KIAA1698
Protein Name
Integrator complex subunit 5 (Int5)
Other Name
Species
Human
Gene ID
80789
Uniprot
Q6P9B9,
Species.1
Mouse
Gene ID.1
109077
Uniprot.1
Q8CHT3
Species.2
Gene ID.2
Uniprot.2
Cellular Localization
Nucleus membrane; Multi-pass membrane protein . Nucleus . Cytoplasm .
Tissue Expression
Signaling_pathway
Research Areas
Function
Component of the Integrator (INT) complex, a complex involved in the small nuclear RNAs (snRNA) U1 and U2 transcription and in their 3'-box-dependent processing. The Integrator complex is associated with the C-terminal domain (CTD) of RNA polymerase II largest subunit (POLR2A) and is recruited to the U1 and U2 snRNAs genes (Probable). Mediates recruitment of cytoplasmic dynein to the nuclear envelope, probably as component of the INT complex .