Background:
The KLHL1 protein belongs to a family of actin-organizing proteins related to Drosophila Kelch (Nemes et al., 2000 [PubMed 10888605]).[supplied by OMIM, Feb 2010],
Specifications
Size
50μL/100μL
Target
KLHL1
Reactivity
Human
Applications
WB, IF, ELISA
MW(Calculated)
83kD
MW(Observed)
Host Species
Mouse
Isotype
Conjugate/Modification
Unmodified
Recommended Dilution Ratio
WB 1:500-1:2000; IF 1:200-1:1000; ELISA 1:10000; Not yet tested in other applications.
Formulation
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Purification
Affinity purification
Storage
-15°C to -25°C/1 year(Do not lower than -25°C)
Concentration
Clonality
Monoclonal
Clone Number
18B2
Immunogen
Purified recombinant fragment of human KLHL1 expressed in E. Coli.
Specificity
KLHL1 Monoclonal Antibody detects endogenous levels of KLHL1 protein.
Gene Name
KLHL1
Protein Name
Kelch-like protein 1
Other Name
KLHL1; / KIAA1490; / Kelch-like protein 1
Species
Human
Gene ID
57626
Uniprot
Q9NR64,
Species.1
Mouse
Gene ID.1
Uniprot.1
Q9JI74
Species.2
Gene ID.2
Uniprot.2
Cellular Localization
Cytoplasm, cytoskeleton.
Tissue Expression
Highly expressed in brain.
Signaling_pathway
Research Areas
Function
Function:May play a role in organizing the actin cytoskeleton of the brain cells.,similarity:Contains 1 BTB (POZ) domain.,similarity:Contains 6 Kelch repeats.,tissue specificity:Highly expressed in brain.,