Price range: $268.00 through $328.00
Background:
function:Probable substrate-specific adapter of an E3 ubiquitin-protein ligase complex which mediates the ubiquitination and subsequent proteasomal degradation of target proteins., pathway:Protein modification; protein ubiquitination., similarity:Contains 1 BACK (BTB/Kelch associated) domain., similarity:Contains 1 BTB (POZ) domain., similarity:Contains 6 Kelch repeats., subunit:Interacts with cul3.,
| Size | 50μL/100μL |
| Target | KLHL21 |
| Reactivity | Human |
| Applications | WB, IHC, IF, ELISA |
| MW(Calculated) | 67kD |
| MW(Observed) | |
| Host Species | Mouse |
| Isotype | |
| Conjugate/Modification | Unmodified |
| Recommended Dilution Ratio | WB 1:500-1:2000; IHC 1:200-1:1000; ELISA 1:10000; IF 1:50-200 / Note: For IHC, we suggest antigen retrieval with TE buffer pH 9.0 (Cat#WT1004) |
| Formulation | Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide. |
| Purification | Affinity purification |
| Storage | -15°C to -25°C/1 year(Do not lower than -25°C) |
| Concentration | |
| Clonality | Monoclonal |
| Clone Number | 13H5 |
| Immunogen | Purified recombinant fragment of human KLHL21 expressed in E. Coli. |
| Specificity | KLHL21 Monoclonal Antibody detects endogenous levels of KLHL21 protein. |
| Gene Name | KLHL21 |
| Protein Name | Kelch-like protein 21 |
| Other Name | KLHL21; / KIAA0469; / Kelch-like protein 21 |
| Species | Human |
| Gene ID | 9903 |
| Uniprot | Q9UJP4, |
| Species.1 | Mouse |
| Gene ID.1 | |
| Uniprot.1 | Q3U410 |
| Species.2 | |
| Gene ID.2 | |
| Uniprot.2 | |
| Cellular Localization | Cytoplasm, cytoskeleton, spindle . Localizes to the spindle midzone and targets CUL3 to this region. |
| Tissue Expression | Brain,Hepatoma,Hippocampus,Lung carcinoma,PCR rescued clones,Spleen, |
| Signaling_pathway | |
| Research Areas | |
| Function | Function:Probable substrate-specific adapter of an E3 ubiquitin-protein ligase complex which mediates the ubiquitination and subsequent proteasomal degradation of target proteins.,pathway:Protein modification; protein ubiquitination.,similarity:Contains 1 BACK (BTB/Kelch associated) domain.,similarity:Contains 1 BTB (POZ) domain.,similarity:Contains 6 Kelch repeats.,subunit:Interacts with cul3., |
