Name: L-type Ca++ CP γ4 Polyclonal Antibody
SKU: WP5829
Price: 268 USD
Availability: InStock

L-type Ca++ CP γ4 Polyclonal Antibody

Ucallm_WP5829-50

Price range: $268.00 through $328.00

Size

100μl

50μl

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SKU: WP5829-100

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Product details

Background:

calcium voltage-gated channel auxiliary subunit gamma 4(CACNG4) Homo sapiens The protein encoded by this gene is a type I transmembrane AMPA receptor regulatory protein (TARP). TARPs regulate both trafficking and channel gating of the AMPA receptors. This gene is part of a functionally diverse eight-member protein subfamily of the PMP-22/EMP/MP20 family and is located in a cluster with two family members, a type II TARP and a calcium channel gamma subunit. [provided by RefSeq, Dec 2010],

Specifications

Size	50μL/100μL
Target	L-type Ca++ CP γ4
Reactivity	Human, Mouse, Rat
Applications	WB, IHC, IF
MW(Calculated)
MW(Observed)	35kD
Host Species	Rabbit
Isotype	IgG
Conjugate/Modification	Unmodified
Recommended Dilution Ratio	WB 1:1000-2000; IHC 1:200-500; IF 1:50-200 / Note: For IHC, we suggest antigen retrieval with TE buffer pH 9.0 (Cat#WT1004)
Formulation	PBS, pH 7.4, containing 0.5%BSA, 0.02% sodium azide as Preservative and 50% Glycerol.
Purification	The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Storage	-15°C to -25°C/1 year(Do not lower than -25°C)
Concentration
Clonality	Polyclonal
Clone Number
Immunogen	Synthetic Peptide of L-type Ca++ CP γ4 AA range: 120-200
Specificity	The antibody detects endogenous L-type Ca++ CP γ4 protein.
Gene Name	CACNG4
Protein Name	Voltage-dependent calcium channel gamma-4 subunit
Other Name	CACNG4; / Voltage-dependent calcium channel gamma-4 subunit; / Neuronal voltage-gated calcium channel gamma-4 subunit; / Transmembrane AMPAR regulatory protein gamma-4; / TARP gamma-4
Species	Human
Gene ID	27092
Uniprot	Q9UBN1,
Species.1	Mouse
Gene ID.1
Uniprot.1	Q9JJV4,
Species.2	Rat
Gene ID.2
Uniprot.2	Q8VHW9
Cellular Localization	Cell membrane; Multi-pass membrane protein .
Tissue Expression	Detected in heart left ventricle.
Signaling_pathway	Organismal Systems >> Endocrine system >> Oxytocin signaling pathway;Organismal Systems >> Circulatory system >> Cardiac muscle contraction;Organismal Systems >> Circulatory system >> Adrenergic signaling in cardiomyocytes;Environmental Information Processing >> Signal transduction >> MAPK signaling pathway
Research Areas	>>MAPK signaling pathway; / >>Cardiac muscle contraction; / >>Adrenergic signaling in cardiomyocytes; / >>Oxytocin signaling pathway; / >>Hypertrophic cardiomyopathy; / >>Arrhythmogenic right ventricular cardiomyopathy; / >>Dilated cardiomyopathy
Function	Function:Thought to stabilize the calcium channel in an inactivated (closed) state.,similarity:Belongs to the PMP-22/EMP/MP20 family. CACNG subfamily.,subunit:The L-type calcium channel is composed of five subunits: alpha-1, alpha-2/delta, beta and gamma.,

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L-type Ca++ CP γ4 Polyclonal Antibody

Product details

Specifications

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L-type Ca++ CP γ4 Polyclonal Antibody

Product details

Specifications

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