LAMP5 rabbit pAb
Product details
Background:
Specifications
| Size | 50μL/100μL |
| Target | LAMP5 |
| Reactivity | Human, Mouse, Rat |
| Applications | WB |
| MW(Calculated) | 31kD |
| MW(Observed) | |
| Host Species | Rabbit |
| Isotype | IgG |
| Conjugate/Modification | Unmodified |
| Recommended Dilution Ratio | WB 1:500-2000 |
| Formulation | Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide. |
| Purification | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Storage | -15°C to -25°C/1 year(Do not lower than -25°C) |
| Concentration | 1 mg/ml |
| Clonality | Polyclonal |
| Clone Number | |
| Immunogen | Synthesized peptide derived from human LAMP5 AA range: 143-193 |
| Specificity | This antibody detects endogenous levels of LAMP5 at Human/Mouse/Rat |
| Gene Name | LAMP5 C20orf103 |
| Protein Name | LAMP5 |
| Other Name | |
| Species | Human |
| Gene ID | 24141 |
| Uniprot | Q9UJQ1, |
| Species.1 | Mouse |
| Gene ID.1 | 76161 |
| Uniprot.1 | Q9D387, |
| Species.2 | Rat |
| Gene ID.2 | 362220 |
| Uniprot.2 | Q5PPI4 |
| Cellular Localization | Cell membrane; Single-pass type I membrane protein . Cytoplasmic vesicle, secretory vesicle, synaptic vesicle membrane; Single-pass type I membrane protein . Endoplasmic reticulum-Golgi intermediate compartment membrane; Single-pass type I membrane protein . Endosome membrane; Single-pass type I membrane protein . Cytoplasmic vesicle membrane; Single-pass type I membrane protein . Cell projection, dendrite . Cell projection, growth cone membrane; Single-pass type I membrane protein . Early endosome membrane; Single-pass type I membrane protein . Recycling endosome . Recycles from the vesicles of the endocytic recycling compartment (ERC) to the plasma membrane (By similarity). Colocalizes with UNC93B1 in large endosomal intracellular vesicles (PubMed:21642595). Accumulates in the endoplasmic reticulum-Golgi intermediate compartment (ERGIC) before its disappearance upon activation by CpG dinucleotides (PubMed:21642595). Associates with cortical membranes (PubMed:21642595). Localizes mostly in cytoplasmic vesicles of neuronal cell body (By similarity). Localizes to synaptic vesicles in a subset of GABAergic neurons (By similarity). . |
| Tissue Expression | Expressed in plasmocytoid dendritic cells. Expressed in suprabasal skin keratinocytes and squamous cells (at protein level). Expressed in the brain and weakly in spleen and skin. Expressed in plasmocytoid dendritic cells. |
| Signaling_pathway | |
| Research Areas | |
| Function | similarity:Belongs to the LAMP family., |
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