Price range: $268.00 through $328.00
Background:
catalytic activity:ATP + a protein = ADP + a phosphoprotein., cofactor:Magnesium or manganese., enzyme regulation:Binding of GTP stimulates kinase activity., PTM:Autophosphorylated., similarity:Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. ROCO subfamily., similarity:Contains 1 protein kinase domain., similarity:Contains 1 Roc domain., similarity:Contains 11 LRR (leucine-rich) repeats., similarity:Contains 4 ANK repeats.,
| Size | 50μL/100μL |
| Target | LRRK1 |
| Reactivity | Human, Mouse |
| Applications | IHC, IF, ELISA |
| MW(Calculated) | 228kD |
| MW(Observed) | |
| Host Species | Rabbit |
| Isotype | IgG |
| Conjugate/Modification | Unmodified |
| Recommended Dilution Ratio | IHC 1:100-1:300; IF 1:200-1:1000; ELISA 1:5000; Not yet tested in other applications. / Note: For IHC, we suggest antigen retrieval with TE buffer pH 9.0 (Cat#WT1004) |
| Formulation | Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide. |
| Purification | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Storage | -15°C to -25°C/1 year(Do not lower than -25°C) |
| Concentration | 1 mg/ml |
| Clonality | Polyclonal |
| Clone Number | |
| Immunogen | The antiserum was produced against synthesized peptide derived from human LRRK1. AA range:361-410 |
| Specificity | LRRK1 Polyclonal Antibody detects endogenous levels of LRRK1 protein. |
| Gene Name | LRRK1 |
| Protein Name | Leucine-rich repeat serine/threonine-protein kinase 1 |
| Other Name | LRRK1; / KIAA1790; / Leucine-rich repeat serine/threonine-protein kinase 1 |
| Species | Human |
| Gene ID | 79705 |
| Uniprot | Q38SD2, |
| Species.1 | Mouse |
| Gene ID.1 | |
| Uniprot.1 | Q3UHC2 |
| Species.2 | |
| Gene ID.2 | |
| Uniprot.2 | |
| Cellular Localization | Cytoplasm . |
| Tissue Expression | Brain,Cervix,Lung,Macrophage,Pancreas,Skin,Spleen, |
| Signaling_pathway | |
| Research Areas | |
| Function | Catalytic activity:ATP + a protein = ADP + a phosphoprotein.,cofactor:Magnesium or manganese.,enzyme regulation:Binding of GTP stimulates kinase activity.,PTM:Autophosphorylated.,similarity:Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. ROCO subfamily.,similarity:Contains 1 protein kinase domain.,similarity:Contains 1 Roc domain.,similarity:Contains 11 LRR (leucine-rich) repeats.,similarity:Contains 4 ANK repeats., |
