Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Purification
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Storage
-15°C to -25°C/1 year(Do not lower than -25°C)
Concentration
1 mg/ml
Clonality
Polyclonal
Clone Number
Immunogen
Synthesized peptide derived from human LSM5
Specificity
This antibody detects endogenous levels of LSM5 at Human, Mouse
Gene Name
LSM5
Protein Name
U6 snRNA-associated Sm-like protein LSm5
Other Name
Species
Human
Gene ID
23658
Uniprot
Q9Y4Y9,
Species.1
Mouse
Gene ID.1
100044729
Uniprot.1
P62322
Species.2
Gene ID.2
Uniprot.2
Cellular Localization
Nucleus .
Tissue Expression
Signaling_pathway
Genetic Information Processing >> Folding, sorting and degradation >> RNA degradation
Research Areas
Function
Plays role in pre-mRNA splicing as component of the U4/U6-U5 tri-snRNP complex that is involved in spliceosome assembly, and as component of the precatalytic spliceosome (spliceosome B complex) . The heptameric LSM2-8 complex binds specifically to the 3'-terminal U-tract of U6 snRNA .