Price range: $268.00 through $328.00
Background:
Melan-A, also known as melanoma antigen recognized by T cell 1, is related to endoplasmic reticulum and melanosomes. It is mainly used for the study of melanoma. Melan A is expressed in all normal melanocytes and melanocyte lines. Tumor cells from epithelium, lymph, glia and mesenchymal origin are generally not expressed. It is mainly used for the diagnosis and differential diagnosis of malignant melanoma and tumors with melanocyte differentiation.
| Size | 50μL/100μL |
| Target | Melan-A |
| Reactivity | Human |
| Applications | IHC, WB, IF, ELISA |
| MW(Calculated) | 13kD |
| MW(Observed) | 18kD |
| Host Species | Mouse |
| Isotype | IgG2b,Kappa |
| Conjugate/Modification | Unmodified |
| Recommended Dilution Ratio | IHC 1:200-1000; WB 1:500-2000; IF 1:100-500; ELISA 1:1000-5000 / Note: For IHC, we suggest antigen retrieval with TE buffer pH 9.0 (Cat#WT1004) |
| Formulation | PBS, 50% glycerol, 0.05% Proclin 300, 0.05%BSA |
| Purification | Recombinant Antibody expressed in animal component-free (ACF) media, purified via Protein G affinity chromatography. |
| Storage | -15°C to -25°C/1 year(Do not lower than -25°C) |
| Concentration | |
| Clonality | Monoclonal |
| Clone Number | RMM-Mart1 |
| Immunogen | Synthesized peptide derived from human Mart-1/Melan-A AA range: 50-118 |
| Specificity | The antibody can specifically recognize human Melan-A protein. |
| Gene Name | MLANA MART1 |
| Protein Name | Mart-1/Melan-A |
| Other Name | Antigen LB39 AA; / Antigen LB39-AA; / Antigen SK29 AA; / Antigen SK29-AA; / MAR1_HUMAN; / MART 1; / MART-1; / MART1; / Melan A; / Melan A protein; / Melanoma antigen recognized by T cells 1; / Melanoma antigen recognized by T-cells 1; / MLAN A; / MLANA; / OTTHUMP00000021036; / OTTHUMP00000021037; / OTTHUMP00000021038; / Protein Melan-A |
| Species | Human |
| Gene ID | 2315 |
| Uniprot | Q16655 |
| Species.1 | |
| Gene ID.1 | |
| Uniprot.1 | |
| Species.2 | |
| Gene ID.2 | |
| Uniprot.2 | |
| Cellular Localization | Cytoplasmic |
| Tissue Expression | Expression is restricted to melanoma and melanocyte cell lines and retina. |
| Signaling_pathway | |
| Research Areas | |
| Function | tissue specificity:Expression is restricted to melanoma and melanocyte cell lines and retina., |
