Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Purification
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Storage
-15°C to -25°C/1 year(Do not lower than -25°C)
Concentration
1 mg/ml
Clonality
Polyclonal
Clone Number
Immunogen
Synthesized peptide derived from human MLXIP
Specificity
This antibody detects endogenous levels of MLXIP at Human, Mouse
Gene Name
MLXIP BHLHE36 KIAA0867 MIR MONDOA
Protein Name
MLX-interacting protein (Class E basic helix-loop-helix protein 36) (bHLHe36) (Transcriptional activator MondoA)
Other Name
Species
Human
Gene ID
22877
Uniprot
Q9HAP2,
Species.1
Mouse
Gene ID.1
208104
Uniprot.1
Q2VPU4
Species.2
Gene ID.2
Uniprot.2
Cellular Localization
Cytoplasm . Nucleus . Mitochondrion outer membrane . Predominantly cytoplasmic but shuttles between cytoplasm and nucleus when associated with MLX. Also associates with the outer mitochondrial membrane and may shuttle between the outer mitochondrial membrane and the nucleus. .
Tissue Expression
Widely expressed in adult tissues. Most abundant in skeletal muscle.
Signaling_pathway
Research Areas
Function
Binds DNA as a heterodimer with MLX and activates transcription. Binds to the canonical E box sequence 5'-CACGTG-3'. Plays a role in transcriptional activation of glycolytic target genes. Involved in glucose-responsive gene regulation.