Price range: $268.00 through $328.00
Background:
The protein encoded by this gene is similar to the yeast Mob1 protein. Yeast Mob1 binds Mps1p, a protein kinase essential for spindle pole body duplication and mitotic checkpoint regulation. Three transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Sep 2011],
| Size | 50μL/100μL |
| Target | MOB1A/B |
| Reactivity | Human, Mouse, Monkey |
| Applications | WB, IHC, IF, ELISA |
| MW(Calculated) | |
| MW(Observed) | 25kD |
| Host Species | Rabbit |
| Isotype | IgG |
| Conjugate/Modification | Unmodified |
| Recommended Dilution Ratio | WB 1:500-1:2000; IHC 1:100-1:300; ELISA 1:40000; IF 1:50-200 / Note: For IHC, we suggest antigen retrieval with TE buffer pH 9.0 (Cat#WT1004) |
| Formulation | Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide. |
| Purification | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Storage | -15°C to -25°C/1 year(Do not lower than -25°C) |
| Concentration | 1 mg/ml |
| Clonality | Polyclonal |
| Clone Number | |
| Immunogen | The antiserum was produced against synthesized peptide derived from human MOL1A. AA range:101-150 |
| Specificity | Mob1A Polyclonal Antibody detects endogenous levels of Mob1A protein. |
| Gene Name | MOB1B |
| Protein Name | MOB kinase activator 1B |
| Other Name | MOB1B; / MOB4A; / MOBKL1A; / MOB kinase activator 1B; / Mob1 homolog 1A; / Mob1A; / Mob1B; / Mps one binder kinase activator-like 1A |
| Species | Human |
| Gene ID | 92597 |
| Uniprot | Q9H8S9;Q7L9L4, |
| Species.1 | Mouse |
| Gene ID.1 | 68473 |
| Uniprot.1 | Q921Y0;Q8BPB0, |
| Species.2 | Rat |
| Gene ID.2 | 297387 |
| Uniprot.2 | Q3T1J9 |
| Cellular Localization | Cytoplasm . Nucleus . |
| Tissue Expression | Adrenal gland, bone marrow, brain, lung, placenta, prostate, salivary gland, skeletal muscle, testis, thymus, thyroid gland, uterus, colon with mucosa, fetal brain and fetal liver. |
| Signaling_pathway | Environmental Information Processing >> Signal transduction >> Hippo signaling pathway;Environmental Information Processing >> Signal transduction >> Hippo signaling pathway - multiple species |
| Research Areas | >>Hippo signaling pathway; / >>Hippo signaling pathway - multiple species |
| Function | Function:Stimulates the kinase activity of STK38L.,similarity:Belongs to the MOB1/phocein family.,subunit:Binds STK38L., |
