Price range: $268.00 through $328.00
Background:The protein encoded by this gene is a high affinity calcium ion-binding protein that is structurally and functionally similar to calmodulin and troponin C. The encoded protein is thought to be involved in muscle relaxation. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Oct 2015],
| Size | 50μL/100μL |
| Target | Parvalbumin |
| Reactivity | Human, Mouse, Rat |
| Applications | WB, IHC, IF, IP, ELISA |
| MW(Calculated) | 12kD |
| MW(Observed) | 12kD |
| Host Species | Rabbit |
| Isotype | IgG,Kappa |
| Conjugate/Modification | Unmodified |
| Recommended Dilution Ratio | IHC 1:2000-1:10000; WB 1:2000-1:10000; IF 1:200-1:1000; ELISA 1:5000-1:20000; IP 1:50-1:200; / Note: For IHC, we suggest antigen retrieval with TE buffer pH 9.0 (Cat#WT1004) |
| Formulation | PBS, 50% glycerol, 0.05% Proclin 300, 0.05%BSA |
| Purification | Recombinant Antibody expressed in animal component-free (ACF) media, purified via Protein A affinity chromatography. |
| Storage | -15°C to -25°C/1 year(Do not lower than -25°C) |
| Concentration | |
| Clonality | Monoclonal |
| Clone Number | RM0155R |
| Immunogen | The specific immunogen used to produce this antibody is proprietary information. |
| Specificity | Endogenous |
| Gene Name | PVALB |
| Protein Name | Parvalbumin alpha |
| Other Name | UBA52; / UBCEP2; / Ubiquitin-60S ribosomal protein L40; / CEP52; / Ubiquitin A-52 residue ribosomal protein fusion product 1 |
| Species | Human |
| Gene ID | 7311 |
| Uniprot | P20472, |
| Species.1 | Mouse |
| Gene ID.1 | |
| Uniprot.1 | P32848, |
| Species.2 | Rat |
| Gene ID.2 | 64156 |
| Uniprot.2 | P62986 |
| Cellular Localization | Cytoplasm |
| Tissue Expression | Brain,Epithelium,Fetal brain cortex,Liver,L |
| Signaling_pathway | Cellular Processes >> Transport and catabolism >> Autophagy - animal;Cellular Processes >> Transport and catabolism >> Mitophagy - animal;Human Diseases >> Neurodegenerative disease >> Parkinson disease;Human Diseases >> Neurodegenerative disease >> Pathways of neurodegeneration - multiple diseases;Genetic Information Processing >> Folding, sorting and degradation >> Ubiquitin mediated proteolysis |
| Research Areas | >>Ribosome; / >>Ubiquitin mediated proteolysis; / >>Mitophagy - animal; / >>Parkinson disease; / >>Pathways of neurodegeneration - multiple diseases; / >>Shigellosis; / >>Kaposi sarcoma-associated herpesvirus infection; / >>Coronavirus disease - COVID-19 |
| Function | Function:In muscle, the calcium-binding protein parvalbumin is thought to be involved in muscle relaxation.,mass spectrometry: PubMed:10036163,miscellaneous:This protein binds two calcium ions.,similarity:Belongs to the parvalbumin family.,similarity:Contains 2 EF-hand domains., |
