Price range: $268.00 through $328.00
Background:
This gene encodes a nucleolar protein that contains six RNA-binding motifs. The encoded protein may be involved in regulating ribosome biogenesis. Multiple alternatively spliced variants, encoding the same protein, have been identified.[provided by RefSeq, Apr 2009],
| Size | 50μL/100μL |
| Target | RBM19 |
| Reactivity | Human, Mouse |
| Applications | WB |
| MW(Calculated) | |
| MW(Observed) | 105kD |
| Host Species | Rabbit |
| Isotype | IgG |
| Conjugate/Modification | Unmodified |
| Recommended Dilution Ratio | WB 1:500-2000 |
| Formulation | Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide. |
| Purification | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Storage | -15°C to -25°C/1 year(Do not lower than -25°C) |
| Concentration | 1 mg/ml |
| Clonality | Polyclonal |
| Clone Number | |
| Immunogen | Synthesized peptide derived from human RBM19 AA range: 276-326 |
| Specificity | This antibody detects endogenous levels of RBM19 at Human/Mouse |
| Gene Name | RBM19 KIAA0682 |
| Protein Name | RBM19 |
| Other Name | Probable RNA-binding protein 19; / RNA-binding motif protein 19 |
| Species | Human |
| Gene ID | 9904 |
| Uniprot | Q9Y4C8, |
| Species.1 | Mouse |
| Gene ID.1 | 74111 |
| Uniprot.1 | Q8R3C6 |
| Species.2 | |
| Gene ID.2 | |
| Uniprot.2 | |
| Cellular Localization | Nucleus, nucleolus . Nucleus, nucleoplasm . Cytoplasm . Chromosome . In discrete foci distributed throughout the cytoplasm and nucleoplasm during the 4 to 8 cell stages and the morula stage, but not in the periphery of the nucleolar precursor body (NPB). During blastocyst development, becomes increasingly localized to the nucleolus and less to the cytoplasm. At the late blastocyst stage, localized predominantly in the nucleolus. Localized in the nucleolus during interphase and to the perichromosomal sheath during mitosis. Does not colocalize in the cytoplasm with GW182 in P-bodies. May translocate to the nucleolus upon early embryonic development (By similarity). Colocalizes with NPM1 during interphase. By late prophase, metaphase, anaphase and telophase, associates with the chromosome periphery. By telophase localizes to NPB. . |
| Tissue Expression | Expressed in the crypts of Lieberkuhn of the intestine and in intestinal neoplasia (at protein level). |
| Signaling_pathway | |
| Research Areas | |
| Function | similarity:Belongs to the RRM MRD1 family.,similarity:Contains 6 RRM (RNA recognition motif) domains., |
