SKU: WP8246 Categories: ,

RDH5 rabbit pAb

Price range: $268.00 through $328.00

SKU: WP8246-100
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Product details

Background:

Specifications

Size50μL/100μL
TargetRDH5
ReactivityHuman, Mouse
ApplicationsWB
MW(Calculated)35kD
MW(Observed)
Host SpeciesRabbit
IsotypeIgG
Conjugate/ModificationUnmodified
Recommended Dilution RatioWB 1:500-2000
FormulationLiquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
PurificationThe antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Storage-15°C to -25°C/1 year(Do not lower than -25°C)
Concentration1 mg/ml
ClonalityPolyclonal
Clone Number
ImmunogenSynthesized peptide derived from human RDH5
SpecificityThis antibody detects endogenous levels of RDH5 at Human, Mouse
Gene NameRDH5 RDH1
Protein Name11-cis retinol dehydrogenase (11-cis RDH) (11-cis RoDH) (9-cis retinol dehydrogenase) (9cRDH)
Other Name
SpeciesHuman
Gene ID5959
UniprotQ92781,
Species.1Mouse
Gene ID.119682
Uniprot.1O55240
Species.2
Gene ID.2
Uniprot.2
Cellular LocalizationEndoplasmic reticulum membrane; Multi-pass membrane protein; Lumenal side .
Tissue ExpressionWidely expressed. In the eye, abundant in the retinal pigment epithelium.
Signaling_pathway
Research Areas
FunctionCatalyzes the oxidation of cis-isomers of retinol, including 11-cis-, 9-cis-, and 13-cis-retinol in an NAD-dependent manner . Has no activity towards all-trans retinal (By similarity). Plays a significant role in 11-cis retinol oxidation in the retinal pigment epithelium cells (RPE). Also recognizes steroids (androsterone, androstanediol) as its substrates .
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