Background:The protein encoded by this gene is produced by macrophages and has antiviral activity. This gene is intronless and the encoded protein is secreted. [provided by RefSeq, Sep 2011],
Specifications
Size
100μL
Target
IFNa
Reactivity
Human
Applications
ELISA
MW(Calculated)
MW(Observed)
Host Species
Isotype
IgG2a,Kappa
Conjugate/Modification
Unmodified
Recommended Dilution Ratio
ELISA 1:5000-100000
Formulation
Phosphate-buffered solution
Purification
Recombinant Expression and Affinity purified
Storage
-15°C to -25°C/1 year(Avoid freeze / thaw cycles)
Concentration
Please check the information on the tube
Clonality
Clone Number
VF0541
Immunogen
Purified recombinant Human IFNa
Specificity
This recombinant monoclonal antibody can detects endogenous levels of IFNa protein.
Cellular Processes >> Cell growth and death >> Necroptosis;Organismal Systems >> Immune system >> Toll-like receptor signaling pathway;Organismal Systems >> Immune system >> NOD-like receptor signaling pathway;Organismal Systems >> Immune system >> RIG-I-like receptor signaling pathway;Organismal Systems >> Immune system >> Cytosolic DNA-sensing pathway;Organismal Systems >> Immune system >> Natural killer cell mediated cytotoxicity;Human Diseases >> Cancer: overview >> Pathways in cancer;Human Diseases >> Immune disease >> Autoimmune thyroid disease;Environmental Information Processing >> Signal transduction >> JAK-STAT signaling pathway;Environmental Information Processing >> Signal transduction >> PI3K-Akt signaling pathway;Environmental Information Processing >> Signaling molecules and interaction >> Cytokine-cytokine receptor interaction
Research Areas
Function
Function:Produced by macrophages, IFN-alpha have antiviral activities. Interferon stimulates the production of two enzymes: a protein kinase and an oligoadenylate synthetase.,miscellaneous:Interferons alpha-1 and alpha-13 have identical protein sequences.,polymorphism:Two forms exist; alpha-1a (shown here) and alpha-1b.,similarity:Belongs to the alpha/beta interferon family.,