SKU: WN0610 Categories: ,

Recombinant IFN-α1 Fc-Fused Nanobody (VF0457)

$365.00

SKU: WN0610
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Product details

Background:The protein encoded by this gene is produced by macrophages and has antiviral activity. This gene is intronless and the encoded protein is secreted. [provided by RefSeq, Sep 2011],

Specifications

Size100μL
TargetIFNa
ReactivityHuman
ApplicationsELISA
MW(Calculated)
MW(Observed)
Host Species
IsotypeIgG2a,Kappa
Conjugate/ModificationUnmodified
Recommended Dilution RatioELISA 1:5000-100000
FormulationPhosphate-buffered solution
PurificationRecombinant Expression and Affinity purified
Storage-15°C to -25°C/1 year(Avoid freeze / thaw cycles)
ConcentrationPlease check the information on the tube
Clonality
Clone NumberVF0541
ImmunogenPurified recombinant Human IFNa
SpecificityThis recombinant monoclonal antibody can detects endogenous levels of IFNa protein.
Gene NameIFNA1/IFNA13
Protein NameInterferon alpha-1/13
Other NameIFNA1; / IFNA13; / Interferon alpha-1/13; / IFN-alpha-1/13; / Interferon alpha-D; / LeIF D; / IFNa nanobody
SpeciesHuman
Gene ID3439
UniprotP01562
Species.1
Gene ID.1
Uniprot.1
Species.2
Gene ID.2
Uniprot.2
Cellular LocalizationSecreted.
Tissue ExpressionLeukocyte,Liver,Placenta,Skin
Signaling_pathwayCellular Processes >> Cell growth and death >> Necroptosis;Organismal Systems >> Immune system >> Toll-like receptor signaling pathway;Organismal Systems >> Immune system >> NOD-like receptor signaling pathway;Organismal Systems >> Immune system >> RIG-I-like receptor signaling pathway;Organismal Systems >> Immune system >> Cytosolic DNA-sensing pathway;Organismal Systems >> Immune system >> Natural killer cell mediated cytotoxicity;Human Diseases >> Cancer: overview >> Pathways in cancer;Human Diseases >> Immune disease >> Autoimmune thyroid disease;Environmental Information Processing >> Signal transduction >> JAK-STAT signaling pathway;Environmental Information Processing >> Signal transduction >> PI3K-Akt signaling pathway;Environmental Information Processing >> Signaling molecules and interaction >> Cytokine-cytokine receptor interaction
Research Areas
FunctionFunction:Produced by macrophages, IFN-alpha have antiviral activities. Interferon stimulates the production of two enzymes: a protein kinase and an oligoadenylate synthetase.,miscellaneous:Interferons alpha-1 and alpha-13 have identical protein sequences.,polymorphism:Two forms exist; alpha-1a (shown here) and alpha-1b.,similarity:Belongs to the alpha/beta interferon family.,
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