SKU: WP4017 Categories: ,

RFX4 rabbit pAb

Price range: $268.00 through $328.00

SKU: WP4017-100
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Product details

Background:

This gene is a member of the regulatory factor X gene family, which encodes transcription factors that contain a highly-conserved winged helix DNA binding domain. The protein encoded by this gene is structurally related to regulatory factors X1, X2, X3, and X5. It has been shown to interact with itself as well as with regulatory factors X2 and X3, but it does not interact with regulatory factor X1. Alternative splicing results in multiple transcript variants. [provided by RefSeq, May 2011],

Specifications

Size50μL/100μL
TargetRFX4
ReactivityHuman, Mouse
ApplicationsWB
MW(Calculated)81kD
MW(Observed)
Host SpeciesRabbit
IsotypeIgG
Conjugate/ModificationUnmodified
Recommended Dilution RatioWB 1:500-2000
FormulationLiquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
PurificationThe antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Storage-15°C to -25°C/1 year(Do not lower than -25°C)
Concentration1 mg/ml
ClonalityPolyclonal
Clone Number
ImmunogenSynthesized peptide derived from human RFX4 AA range: 439-489
SpecificityThis antibody detects endogenous levels of RFX4 at Human/Mouse
Gene NameRFX4
Protein NameRFX4
Other Name
SpeciesHuman
Gene ID5992
UniprotQ33E94,
Species.1Mouse
Gene ID.171137
Uniprot.1Q7TNK1
Species.2
Gene ID.2
Uniprot.2
Cellular LocalizationNucleus .
Tissue ExpressionIsoform 1: Expressed in brain and gliomas (at protein level). Isoform 2: Testis-specific (at protein level). Isoform 3: Testis-specific (at protein level). Isoform 3: Expressed at a higher level in adult testes and ejaculated spematozoa than in fetal testes. Isoform 4: Testis-specific.
Signaling_pathway
Research Areas
FunctionFunction:May activate transcription by interacting directly with the X-box.,similarity:Belongs to the RFX family.,subunit:Homodimer. Heterodimer with RFX2 and RFX3. Binds DNA.,tissue specificity:Isoform 4 is testis-specific. Isoform 1 is expressed in brain and gliomas. Isoform 2 and isoform 3 are testis-specific (at protein level). Isoform 1 is expressed in brain (at protein level). Isoform 3 is expressed at a higher level in adult testes and ejaculated spematozoa than in fetal testes.,
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