Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Purification
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Storage
-15°C to -25°C/1 year(Do not lower than -25°C)
Concentration
1 mg/ml
Clonality
Polyclonal
Clone Number
Immunogen
Synthesized peptide derived from human RGL3 AA range: 601-651
Specificity
This antibody detects endogenous levels of RGL3 at Human/Mouse
Gene Name
RGL3
Protein Name
RGL3
Other Name
Species
Human
Gene ID
57139
Uniprot
Q3MIN7,
Species.1
Mouse
Gene ID.1
71746
Uniprot.1
Q3UYI5
Species.2
Gene ID.2
Uniprot.2
Cellular Localization
intracellular,
Tissue Expression
Signaling_pathway
Research Areas
Function
Domain:The Ras-associating domain plays a central role in the activation of Ral-A GDP/GTP exchange activity.,Function:Guanine nucleotide exchange factor (GEF) for Ral-A. Potential effector of GTPase HRas and Ras-related protein M-Ras. Negatively regulates Elk-1-dependent gene induction downstream of HRas and MEKK1.,similarity:Contains 1 N-terminal Ras-GEF domain.,similarity:Contains 1 Ras-associating domain.,similarity:Contains 1 Ras-GEF domain.,subunit:Interacts with GTP-bound forms of RIT1, HRAS and MRAS.,