Price range: $268.00 through $328.00
Background:
The protein encoded by this gene belongs to the Rho family of the small GTPase superfamily. It contains a GTPase domain, a proline-rich region, a tandem of 2 BTB (broad complex, tramtrack, and bric-a-brac) domains, and a conserved C-terminal region. The protein plays a role in small GTPase-mediated signal transduction and the organization of the actin filament system. Alternate splicing results in multiple transcript variants. [provided by RefSeq, Dec 2008],
| Size | 50μL/100μL |
| Target | RhoBTB1/2 |
| Reactivity | Human, Mouse |
| Applications | WB, IHC, IF, ELISA |
| MW(Calculated) | |
| MW(Observed) | 83kD |
| Host Species | Rabbit |
| Isotype | IgG |
| Conjugate/Modification | Unmodified |
| Recommended Dilution Ratio | WB 1:500-1:2000; IHC 1:100-1:300; IF 1:200-1:1000; ELISA 1:5000; Not yet tested in other applications. / Note: For IHC, we suggest antigen retrieval with TE buffer pH 9.0 (Cat#WT1004) |
| Formulation | Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide. |
| Purification | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Storage | -15°C to -25°C/1 year(Do not lower than -25°C) |
| Concentration | 1 mg/ml |
| Clonality | Polyclonal |
| Clone Number | |
| Immunogen | The antiserum was produced against synthesized peptide derived from human RHBT2. AA range:61-110 |
| Specificity | RhoBTB1/2 Polyclonal Antibody detects endogenous levels of RhoBTB1/2 protein. |
| Gene Name | RHOBTB1/RHOBTB2 |
| Protein Name | Rho-related BTB domain-containing protein 1/2 |
| Other Name | RHOBTB1; / KIAA0740; / Rho-related BTB domain-containing protein 1; / RHOBTB2; / DBC2; / KIAA0717; / Rho-related BTB domain-containing protein 2; / Deleted in breast cancer 2 gene protein; / p83 |
| Species | Human |
| Gene ID | 23221;9886 |
| Uniprot | O94844;Q9BYZ6, |
| Species.1 | Mouse |
| Gene ID.1 | 69288;246710 |
| Uniprot.1 | |
| Species.2 | |
| Gene ID.2 | |
| Uniprot.2 | |
| Cellular Localization | intracellular,cytosol,plasma membrane, |
| Tissue Expression | Ubiquitous, with highest levels in skeletal muscle, placenta, testis, stomach, and kidney, followed by uterus and adrenal gland. Expressed in a variety of fetal tissues. |
| Signaling_pathway | |
| Research Areas | >>Ubiquitin mediated proteolysis |
| Function | similarity:Belongs to the small GTPase superfamily. Rho family.,similarity:Contains 2 BTB (POZ) domains.,tissue specificity:Ubiquitous, with highest levels in skeletal muscle, placenta, testis, stomach, and kidney, followed by uterus and adrenal gland. Expressed in a variety of fetal tissues., |
