Price range: $268.00 through $328.00
Background:
domain:The PDZ domain mediates interaction with ROPN1., function:Has no enzymatic activity. May serve as a target for Rho, and interact with some cytoskeletal component upon Rho binding or relay a Rho signal to other molecules., similarity:Belongs to the RHPN family., similarity:Contains 1 BRO1 domain., similarity:Contains 1 PDZ (DHR) domain., similarity:Contains 1 REM (Hr1) repeat., subunit:Binds specifically to GTP-Rho. Interacts with ROPN1.,
| Size | 50μL/100μL |
| Target | Rhophilin |
| Reactivity | Human, Mouse |
| Applications | WB, ELISA, IHC |
| MW(Calculated) | |
| MW(Observed) | 100kD |
| Host Species | Rabbit |
| Isotype | IgG |
| Conjugate/Modification | Unmodified |
| Recommended Dilution Ratio | WB 1:500-2000; IHC 1:50-300; ELISA 1:2000-20000 / Note: For IHC, we suggest antigen retrieval with TE buffer pH 9.0 (Cat#WT1004) |
| Formulation | Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide. |
| Purification | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Storage | -15°C to -25°C/1 year(Do not lower than -25°C) |
| Concentration | 1 mg/ml |
| Clonality | Polyclonal |
| Clone Number | |
| Immunogen | The antiserum was produced against synthesized peptide derived from human RHPN1. AA range:474-523 |
| Specificity | Rhophilin Polyclonal Antibody detects endogenous levels of Rhophilin protein. |
| Gene Name | RHPN1 |
| Protein Name | Rhophilin-1 |
| Other Name | RHPN1; / KIAA1929; / Rhophilin-1; / GTP-Rho-binding protein 1 |
| Species | Human |
| Gene ID | 114822 |
| Uniprot | Q8TCX5, |
| Species.1 | Mouse |
| Gene ID.1 | |
| Uniprot.1 | Q61085 |
| Species.2 | |
| Gene ID.2 | |
| Uniprot.2 | |
| Cellular Localization | cytosol, |
| Tissue Expression | Blood,Brain, |
| Signaling_pathway | |
| Research Areas | |
| Function | Domain:The PDZ domain mediates interaction with ROPN1.,Function:Has no enzymatic activity. May serve as a target for Rho, and interact with some cytoskeletal component upon Rho binding or relay a Rho signal to other molecules.,similarity:Belongs to the RHPN family.,similarity:Contains 1 BRO1 domain.,similarity:Contains 1 PDZ (DHR) domain.,similarity:Contains 1 REM (Hr1) repeat.,subunit:Binds specifically to GTP-Rho. Interacts with ROPN1., |
