SKU: WP14325 Categories: ,

Ribosomal Protein S18 Polyclonal Antibody

Price range: $268.00 through $328.00

SKU: WP14325-100
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Product details

Background:

Ribosomes, the organelles that catalyze protein synthesis, consist of a small 40S subunit and a large 60S subunit. Together these subunits are composed of 4 RNA species and approximately 80 structurally distinct proteins. This gene encodes a ribosomal protein that is a component of the 40S subunit. The protein belongs to the S13P family of ribosomal proteins. It is located in the cytoplasm. The gene product of the E. coli ortholog (ribosomal protein S13) is involved in the binding of fMet-tRNA, and thus, in the initiation of translation. This gene is an ortholog of mouse Ke3. As is typical for genes encoding ribosomal proteins, there are multiple processed pseudogenes of this gene dispersed through the genome. [provided by RefSeq, Jul 2008],

Specifications

Size50μL/100μL
TargetRibosomal Protein S18
ReactivityHuman, Mouse, Rat
ApplicationsWB, ELISA, IHC
MW(Calculated)
MW(Observed)18kD
Host SpeciesRabbit
IsotypeIgG
Conjugate/ModificationUnmodified
Recommended Dilution RatioWB 1:500-2000; IHC 1:50-300; ELISA 1:2000-20000 / Note: For IHC, we suggest antigen retrieval with TE buffer pH 9.0 (Cat#WT1004)
FormulationLiquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
PurificationThe antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Storage-15°C to -25°C/1 year(Do not lower than -25°C)
Concentration1 mg/ml
ClonalityPolyclonal
Clone Number
ImmunogenSynthesized peptide derived from Ribosomal Protein S18 . at AA range: 50-130
SpecificityRibosomal Protein S18 Polyclonal Antibody detects endogenous levels of Ribosomal Protein S18 protein.
Gene NameRPS18
Protein Name40S ribosomal protein S18
Other NameRPS18; / D6S218E; / 40S ribosomal protein S18; / Ke-3; / Ke3
SpeciesHuman
Gene ID6222
UniprotP62269,
Species.1Mouse
Gene ID.120084
Uniprot.1P62270,
Species.2Rat
Gene ID.2294282
Uniprot.2P62271
Cellular LocalizationCytoplasm.
Tissue ExpressionBone,Brain,Colon carcinoma,Embryonal rhabdomyosarcoma,Placenta,
Signaling_pathway
Research Areas>>Ribosome; / >>Coronavirus disease - COVID-19
FunctionFunction:Located at the top of the head of the 40S subunit, it contacts several helices of the 18S rRNA.,similarity:Belongs to the ribosomal protein S13P family.,
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