Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Purification
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Storage
-15°C to -25°C/1 year(Do not lower than -25°C)
Concentration
1 mg/ml
Clonality
Polyclonal
Clone Number
Immunogen
Synthesized peptide derived from human RNASEH2A
Specificity
This antibody detects endogenous levels of RNASEH2A at Human, Mouse,Rat
Gene Name
RNASEH2A RNASEHI RNHIA
Protein Name
Ribonuclease H2 subunit A (RNase H2 subunit A) (Aicardi-Goutieres syndrome 4 protein) (AGS4) (RNase H(35)) (Ribonuclease HI large subunit) (RNase HI large subunit) (Ribonuclease HI subunit A)
Other Name
Species
Human
Gene ID
10535
Uniprot
O75792,
Species.1
Mouse
Gene ID.1
69724
Uniprot.1
Q9CWY8,
Species.2
Rat
Gene ID.2
364974
Uniprot.2
Q5U209
Cellular Localization
Nucleus .
Tissue Expression
Signaling_pathway
Research Areas
Function
Catalytic subunit of RNase HII, an endonuclease that specifically degrades the RNA of RNA:DNA hybrids. Participates in DNA replication, possibly by mediating the removal of lagging-strand Okazaki fragment RNA primers during DNA replication. Mediates the excision of single ribonucleotides from DNA:RNA duplexes.