SKU: WP6524 Categories: ,

RNASEH2A rabbit pAb

Price range: $268.00 through $328.00

SKU: WP6524-100
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Product details

Background:

Specifications

Size50μL/100μL
TargetRNASEH2A
ReactivityHuman, Mouse, Rat
ApplicationsWB
MW(Calculated)33kD
MW(Observed)
Host SpeciesRabbit
IsotypeIgG
Conjugate/ModificationUnmodified
Recommended Dilution RatioWB 1:500-2000
FormulationLiquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
PurificationThe antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Storage-15°C to -25°C/1 year(Do not lower than -25°C)
Concentration1 mg/ml
ClonalityPolyclonal
Clone Number
ImmunogenSynthesized peptide derived from human RNASEH2A
SpecificityThis antibody detects endogenous levels of RNASEH2A at Human, Mouse,Rat
Gene NameRNASEH2A RNASEHI RNHIA
Protein NameRibonuclease H2 subunit A (RNase H2 subunit A) (Aicardi-Goutieres syndrome 4 protein) (AGS4) (RNase H(35)) (Ribonuclease HI large subunit) (RNase HI large subunit) (Ribonuclease HI subunit A)
Other Name
SpeciesHuman
Gene ID10535
UniprotO75792,
Species.1Mouse
Gene ID.169724
Uniprot.1Q9CWY8,
Species.2Rat
Gene ID.2364974
Uniprot.2Q5U209
Cellular LocalizationNucleus .
Tissue Expression
Signaling_pathway
Research Areas
FunctionCatalytic subunit of RNase HII, an endonuclease that specifically degrades the RNA of RNA:DNA hybrids. Participates in DNA replication, possibly by mediating the removal of lagging-strand Okazaki fragment RNA primers during DNA replication. Mediates the excision of single ribonucleotides from DNA:RNA duplexes.
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