Price range: $268.00 through $328.00
Background:
This gene encodes a protein which is a member of the small GTPase protein superfamily. The encoded protein binds only GTP but has no GTPase activity, and appears to act as a negative regulator of cytoskeletal organization leading to loss of adhesion. Multiple alternatively spliced variants, encoding the same protein, have been identified. [provided by RefSeq, Dec 2011],
| Size | 50μL/100μL |
| Target | RND3 |
| Reactivity | Human, Mouse, Rat |
| Applications | WB, ELISA |
| MW(Calculated) | |
| MW(Observed) | 26kD |
| Host Species | Rabbit |
| Isotype | IgG |
| Conjugate/Modification | Unmodified |
| Recommended Dilution Ratio | WB 1:500-2000; ELISA 1:5000-20000 |
| Formulation | Liquid in PBS containing 50% glycerol,0.5% BSA and 0.02% sodium azide. |
| Purification | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Storage | -15°C to -25°C/1 year(Do not lower than -25°C) |
| Concentration | 1 mg/ml |
| Clonality | Polyclonal |
| Clone Number | |
| Immunogen | Synthesized peptide derived from human protein . at AA range: 150-230 |
| Specificity | RND3 Polyclonal Antibody detects endogenous levels of protein. |
| Gene Name | RND3 ARHE RHO8 RHOE |
| Protein Name | Rho-related GTP-binding protein RhoE (Protein MemB) (Rho family GTPase 3) (Rho-related GTP-binding protein Rho8) (Rnd3) |
| Other Name | |
| Species | Human |
| Gene ID | 390 |
| Uniprot | P61587, |
| Species.1 | Mouse |
| Gene ID.1 | |
| Uniprot.1 | P61588, |
| Species.2 | Rat |
| Gene ID.2 | |
| Uniprot.2 | Q6SA80 |
| Cellular Localization | Golgi apparatus membrane; Peripheral membrane protein. |
| Tissue Expression | Ubiquitous. |
| Signaling_pathway | |
| Research Areas | |
| Function | Function:Binds GTP but lacks intrinsic GTPase activity and is resistant to Rho-specific GTPase-activating proteins.,similarity:Belongs to the small GTPase superfamily. Rho family.,subunit:Binds ROCK1 (By similarity). Interacts with UBXD5.,tissue specificity:Ubiquitous., |
