RRAGD Polyclonal Antibody
Ucallm_WP1585-50
Price range: $268.00 through $328.00
Product details
Background:
RRAGD is a monomeric guanine nucleotide-binding protein, or G protein. By binding GTP or GDP, small G proteins act as molecular switches in numerous cell processes and signaling pathways.[supplied by OMIM, Apr 2004],
Specifications
| Size | 50μL/100μL |
| Target | RRAGD |
| Reactivity | Human, Mouse |
| Applications | WB, ELISA, CoIP |
| MW(Calculated) | |
| MW(Observed) | 44kD |
| Host Species | Rabbit |
| Isotype | IgG |
| Conjugate/Modification | Unmodified |
| Recommended Dilution Ratio | IP 1:50-200; WB 1:500-2000; ELISA 1:5000-20000 |
| Formulation | Liquid in PBS containing 50% glycerol,0.5% BSA and 0.02% sodium azide. |
| Purification | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Storage | -15°C to -25°C/1 year(Do not lower than -25°C) |
| Concentration | 1 mg/ml |
| Clonality | Polyclonal |
| Clone Number | |
| Immunogen | Synthesized peptide derived from human protein . at AA range: 140-220 |
| Specificity | RRAGD Polyclonal Antibody detects endogenous levels of protein. |
| Gene Name | RRAGD |
| Protein Name | Ras-related GTP-binding protein D (Rag D) (RagD) |
| Other Name | |
| Species | Human |
| Gene ID | 58528 |
| Uniprot | Q9NQL2, |
| Species.1 | Mouse |
| Gene ID.1 | |
| Uniprot.1 | Q7TT45 |
| Species.2 | |
| Gene ID.2 | |
| Uniprot.2 | |
| Cellular Localization | Cytoplasm . Nucleus . Lysosome . Predominantly cytoplasmic. May shuttle between the cytoplasm and nucleus, depending on the bound nucleotide state of associated RRAGA (PubMed:11073942). . |
| Tissue Expression | Amygdala,Lung, |
| Signaling_pathway | Cellular Processes >> Transport and catabolism >> Autophagy - animal;Environmental Information Processing >> Signal transduction >> mTOR signaling pathway |
| Research Areas | >>Autophagy - animal; / >>mTOR signaling pathway; / >>Shigellosis |
| Function | Function:Has guanine nucleotide-binding activity but lacks intrinsic GTPase activity.,similarity:Belongs to the GTR/RAG GTP-binding protein family.,subcellular location:Predominantly cytoplasmic. May shuttle between the cytoplasm and nucleus, depending on the bound nucleotide state of associated RRAGA.,subunit:Forms a heterodimer with RRAGA in a sequence-independent manner. Binds GTP. Interacts with NOL8 and RRAGB., |
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